Prehospital High-Sensitivity Troponin I to rule out heart attack for EMS patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective observational study in the Central Denmark Region tests the feasibility and diagnostic accuracy of measuring high-sensitivity troponin I in prehospital settings using a portable device. Blood is drawn during routine EMS care, analyzed on site, and results are not used to guide treatment. Final hospital diagnoses will be determined by standard medical assessments, including serial troponin testing. The goal is to see if prehospital hs-TnI can help triage patients without ST-elevation chest pain.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 years or older
* Assessed by one of the participating EMS units equipped for POCT sampling
* Presentation with symptoms suggestive of acute coronary syndrome
* Planned transport to hospital for further evaluation

Exclusion Criteria:

* ST-segment elevation on prehospital electrocardiogram
* Clinical condition requiring immediate life-saving intervention precluding study procedures
* Interhospital transport
* Prior inclusion in the study within 30 days

Where it's running

• Prehospital Emergency Medical Services, Central Denamrk Region
  Aarhus N, Denmark Recruiting

Study contacts

• Principal investigator: Martin F Gude, MD, PhD — Central Denmark Region
• Study coordinator: Martin F Gude, MD, PhD
• Email: martgude@rm.dk
• Phone: +45 25 34 36 21

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.