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Clinical trials and research at Shanghai Changzheng Hospital

• 33Clinical trials
• 1Country

Newest trials

All recruiting trials (33)

• Fecal microbiota transplantation for overweight women with PMOS undergoing embryo transfer

  We are testing if oral FMT capsules are safe and can improve pregnancy outcomes for overweight/obese women with PMOS undergoing frozen embryo transfer.

  Recruiting Shanghai Changzheng Hospital · Shanghai, Shanghai Municipality · NCT07746635

• AI-based MRI and ultrasound for thyroid-related eye disease

  This study tests an AI model using orbital MRI and eye ultrasound to help diagnose activity and severity of thyroid-associated ophthalmopathy and predict its course in adults.

  Recruiting Shanghai Changzheng Hospital · Shanghai, Huangpu District · NCT07716397

• KCD Regimen for Newly Diagnosed POEMS Syndrome

  The study tests whether the KCD regimen (carfilzomib, cyclophosphamide, and dexamethasone) is safe and effective in adults newly diagnosed with POEMS syndrome.

  Recruiting Phase 2 Shanghai Changzheng Hospital · Shanghai · NCT07652879

• HIPEC-primed therapy with serplulimab plus SOX/XELOX for locally advanced gastric cancer

  This study tests a HIPEC-priming approach followed by PD-1 blocker–based chemotherapy to see if it helps people with locally advanced gastric cancer who have not yet spread.

  Recruiting Phase 2 Shanghai Changzheng Hospital · Shanghai · NCT07621484

• Radiotherapy after Separation Surgery for Spinal Metastases

  This study tests whether giving radiotherapy after separation surgery helps people with spinal metastases live longer and feel better.

  Recruiting Shanghai Changzheng Hospital · Shanghai, Shanghai Municipality · NCT07527884

• MTS109 treatment for refractory autoimmune diseases

  This trial tests whether MTS109 (an mRNA-LNP given by subcutaneous injection) is safe and tolerable in adults with moderate to severe autoimmune diseases that have not responded to standard treatments.

  Recruiting Early Phase 1 Shanghai Changzheng Hospital · Shanghai, Shanghai Municipality · NCT07526350

• Anlotinib plus sintilimab as first treatment for advanced colorectal cancer without liver metastases

  This study will see if taking anlotinib together with sintilimab as the first treatment helps adults with advanced colorectal cancer that has spread outside the liver who cannot or choose not to have standard chemotherapy.

  Recruiting Phase 2 Shanghai Changzheng Hospital · Shanghai · NCT07398326

• Eye movement and visual attention in people with thyroid-associated eye disease

  This project uses non-invasive eye tracking to test whether people with thyroid-associated ophthalmopathy track moving objects and scan faces differently than healthy volunteers.

  Recruiting Shanghai Changzheng Hospital · Shanghai · NCT07381413

• Rifaximin-α treatment for metabolic dysfunction‑associated steatotic liver disease

  This trial will test whether taking Rifaximin‑α daily for 24 weeks can reduce liver fat and improve metabolic markers in adults with MASLD.

  Recruiting Early Phase 1 Shanghai Changzheng Hospital · Shanghai · NCT07381257

• Tear iron levels and dry eye severity

  This project will see if the amount of iron in tears is linked to how severe someone's dry eye is by comparing people with dry eye to healthy volunteers.

  Recruiting Shanghai Changzheng Hospital · Shanghai · NCT07363824

• Pancreatic enzyme treatment for blood sugar and digestion changes in chronic pancreatitis

  This trial will try pancreatic enzyme capsules (Creon) in adults with chronic pancreatitis and exocrine insufficiency to see if their blood sugar patterns and digestive and gut hormone levels change.

  Recruiting Early Phase 1 Shanghai Changzheng Hospital · Shanghai, Shanghai Municipality and 1 other locations · NCT07314489

• Rifaximin treatment for metabolic-associated fatty liver disease

  This trial tests whether taking oral rifaximin for 24 weeks helps adults with metabolic-associated fatty liver disease (MAFLD) and is safe.

  Recruiting Early Phase 1 Shanghai Changzheng Hospital · Shanghai, Shanghai Municipality · NCT07185932

• IBI311 for inactive thyroid‑related eye disease (TAO)

  This trial tests whether IBI311, an anti–IGF‑1R antibody, can help people with inactive moderate-to-severe thyroid‑associated ophthalmopathy who still have symptoms or need further surgery.

  Recruiting Phase 4 Shanghai Changzheng Hospital · Shanghai, Shanghai Municipality · NCT07152392

• Sequential hormone therapy followed by tetuzumab for moderate-to-severe active thyroid eye disease after steroid treatment

  This trial will test whether adding tetuzumab after prior steroid treatment helps people with moderate-to-severe active thyroid eye disease.

  Recruiting Phase 4 Shanghai Changzheng Hospital · Shanghai, Shanghai Municipality · NCT07152366

• Sequential glucocorticoid therapy followed by IBI311 for active moderate-to-severe thyroid eye disease

  This trial tests whether giving standard glucocorticoids followed by the anti-IGF-1R antibody IBI311 helps adults with active moderate-to-severe thyroid-associated ophthalmopathy (TAO).

  Recruiting Phase 4 Shanghai Changzheng Hospital · Changhua, Shanghai Municipality and 1 other locations · NCT07152340

• Inhaled mesenchymal stem cell–derived exosomes for post-infectious cough

  This trial will try inhaled mesenchymal stem cell–derived exosomes, added to a standard cough medication, in adults 18–60 who have a lingering post-infectious cough to see if it reduces coughing and improves symptoms.

  Recruiting Phase 1/2 Shanghai Changzheng Hospital · Shanghai, Shanghai Municipality · NCT07103980

• Intravenous HNF4α srRNA (CD-GA-102) for unresectable or metastatic colorectal cancer

  This trial will try IV CD-GA-102 (HNF4α srRNA) alone or with other cancer medicines to see if it is safe and can help adults with unresectable or metastatic colorectal cancer who have progressed on or cannot tolerate standard treatments.

  Recruiting Early Phase 1 Shanghai Changzheng Hospital · Shanghai, None Selected · NCT07050394

• Heart, kidney, and metabolic health in Shanghai community residents

  This follow-up will track people from the STONE cohort to see if changes in metabolic risk factors over time relate to heart and kidney outcomes.

  Recruiting Shanghai Changzheng Hospital · Shanghai, Shanghai Municipality · NCT07043166

• Single hiSC injection into the knee for rheumatoid arthritis

  This study will try a single injection of lab-made human Sertoli cells (hiSCs) into an inflamed knee to see if it helps adults with rheumatoid arthritis who still have knee swelling and pain despite standard treatment.

  Recruiting Shanghai Changzheng Hospital · Shanghai · NCT06947746

• Assessing the effectiveness of a new drug combination for advanced colorectal cancer treatment

  This study is testing a new combination of four drugs to see if it can help people with advanced colorectal cancer who haven't had success with other treatments.

  Recruiting Phase 2 Shanghai Changzheng Hospital · Shanghai · NCT06930118

• Combination therapy for locally recurrent colorectal cancer

  This study is testing a new combination of medications to see if it can help people with locally recurrent colorectal cancer who have already had surgery for their initial cancer.

  Recruiting Phase 2 Shanghai Changzheng Hospital · Shanghai · NCT06881537

• Combining stem cells with islet transplantation to treat diabetes

  This study is testing if adding stem cells to islet transplantation can improve diabetes treatment for adults aged 18 to 70.

  Recruiting Shanghai Changzheng Hospital · Shanghai, Shanghai Municipality · NCT06751199

• CT0596 treatment for patients with relapsed or refractory multiple myeloma and plasma cell leukemia

  This study is testing a new CAR-T cell therapy called CT0596 to see if it can help people with relapsed or hard-to-treat multiple myeloma and plasma cell leukemia.

  Recruiting Early Phase 1 Shanghai Changzheng Hospital · Shanghai, Shanghai Municipality · NCT06718270

• Evaluating HNF4α srRNA for treating metastatic colorectal cancer

  This study is testing a new treatment called HNF4α srRNA to see if it is safe and tolerable for people with advanced colorectal cancer that can't be surgically removed.

  Recruiting Early Phase 1 Shanghai Changzheng Hospital · Shanghai, Shanghai Municipality · NCT06621173

• Combination treatment for advanced colorectal cancer with BRAF V600E mutation

  This study is testing a new combination treatment for advanced colorectal cancer with a specific mutation to see if it works better than the usual treatment.

  Recruiting Phase 2 Shanghai Changzheng Hospital · Shanghai · NCT06603376

• Multiparametric prediction models for moderate to severe thyroid-associated eye disease

  This project will try to build and test combined imaging and lab-marker models to predict outcomes in adults with moderate to severe thyroid-associated ophthalmopathy.

  Recruiting Shanghai Changzheng Hospital · Shanghai, Shanghai Municipality · NCT06590220

• Diabetes risk after pancreatic cancer surgery

  This tests how often adults without prior diabetes develop pre-diabetes or diabetes after pancreatic cancer surgery and whether changes in pancreatic hormone and enzyme function affect recovery and overall outcomes.

  Recruiting Shanghai Changzheng Hospital · Shanghai, Shanghai Municipality · NCT06585072

• Evaluating HNF4α srRNA for treating advanced intrahepatic cholangiocarcinoma

  This study is testing a new treatment called HNF4α srRNA to see if it is safe and effective for people with advanced intrahepatic cholangiocarcinoma.

  Recruiting Early Phase 1 Shanghai Changzheng Hospital · Shanghai, Shanghai Municipality · NCT06583993

• Evaluating CD-801 for treating advanced liver cancer

  This study is testing a new treatment called CD-801 to see if it can safely help people with advanced liver cancer feel better and improve their outcomes.

  Recruiting Early Phase 1 Shanghai Changzheng Hospital · Shanghai, Shanghai Municipality · NCT06418659

• CT071 injection for high-risk newly diagnosed multiple myeloma

  This study is testing a new treatment called CT071 to see if it can help people with high-risk newly diagnosed multiple myeloma feel better and manage their condition.

  Recruiting Early Phase 1 Shanghai Changzheng Hospital · Shanghai, Shanghai Municipality · NCT06407947

• Comparing two robotic surgery methods for prostate cancer treatment

  This study is testing which of two robotic surgery methods works better for treating localized prostate cancer and helps patients recover faster.

  Recruiting Shanghai Changzheng Hospital · Shanghai, Shanghai Municipality · NCT06238713

• Comparing two surgical approaches for spinal oligometastatic tumors with radiotherapy

  This study is testing whether two different types of surgery combined with radiation can help people with spinal cancer live longer and feel better.

  Recruiting Shanghai Changzheng Hospital · Shanghai, Shanghai Municipality · NCT06120426

• Using oral prednisone to treat bone Langerhans cell histiocytosis in children and adolescents

  This study is testing if giving oral prednisone can help children and teenagers with bone Langerhans cell histiocytosis feel better compared to just watching their condition.

  Recruiting Phase 2 Shanghai Changzheng Hospital · Shanghai, Shanghai Municipality · NCT06078969

Quick answers

How many clinical trials run by Shanghai Changzheng Hospital are recruiting right now?

33, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in China. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Early Phase 1: 10, Phase 2: 7, Phase 4: 3, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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