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Clinical trials and research at University of Manchester

• 22Clinical trials
• 2NIH research projects
• 3Countries

Newest trials

All recruiting trials (22)

• Inflammation, infection and treatments during severe cystic fibrosis flare-ups

  Researchers will follow people with cystic fibrosis who are at risk of severe lung flare-ups to see if symptoms, lung tests, and biological samples explain different responses to intravenous antibiotics.

  Recruiting University of Manchester · Cardiff and 5 other locations · NCT07484607

• UK multicentre hypertrophic cardiomyopathy registry

  This project collects health information from adults with hypertrophic cardiomyopathy across UK NHS hospitals to see which treatments and tests work best for different patients.

  Recruiting University of Manchester · Manchester · NCT07381894

• Culturally adapted CBT for psychosis in Black people in the UK

  A small series tests whether culturally tailored cognitive-behavioral therapy for psychosis is doable, acceptable, and safe for Black Sub-Saharan African and Caribbean individuals in the UK.

  Recruiting University of Manchester · Manchester · NCT07252206

• Making AI triage more accurate for patients contacting their GP

  This project will test whether updated AI in the Patchs online consultation system can make triage decisions more accurate and fair for patients contacting GP practices in England.

  Recruiting University of Manchester · London · NCT07237919

• Camzyos and heart blood flow in HOCM: a PET imaging study

  This trial tests if Camzyos (mavacamten) can improve blood flow to the heart muscle in people with HOCM who have chest pain or shortness of breath.

  Recruiting University of Manchester · Manchester · NCT07120776

• New sensor for monitoring fetal health during late pregnancy

  This study is testing a new non-adhesive sensor to see if it can accurately monitor the heart rates of pregnant women and their babies during late pregnancy.

  Recruiting University of Manchester · Manchester · NCT06952777

• Causes and risk factors of lung exacerbations in cystic fibrosis

  This project will test whether regular home and clinic sampling can identify causes and triggers of lung exacerbations in people with cystic fibrosis.

  Recruiting at 8 sites University of Manchester · Manchester, Manchester and 17 other locations · NCT06940531

• Evaluating the outcomes of cartilage repair surgery in the knee

  This study is testing how well cartilage repair surgery helps people with knee injuries feel and move better after the operation.

  Recruiting at 4 sites University of Manchester · Birmingham and 6 other locations · NCT06921889

• Using accelerometers to measure physical activity in cancer patients

  This study is testing whether wearing a device that tracks movement can help cancer patients understand their activity levels and fatigue during treatment.

  Recruiting at 4 sites University of Manchester · Milan and 7 other locations · NCT06868355

• Exploring how early life experiences affect brain and behavior

  This study looks at how early life experiences like adoption and trauma affect brain development and behavior in young adults to help identify those at risk for mental health issues later on.

  Recruiting University of Manchester · Manchester · NCT06823492

• Identifying Hypoxic Tumors for Improved Cancer Treatment

  This study is testing a way to find tumors with low oxygen levels in bladder and prostate cancer patients to see if personalizing their treatment can help them respond better to radiotherapy.

  Recruiting University of Manchester · Manchester · NCT06787053

• Understanding heart problems in patients with immune-related diseases

  This study is trying to find out more about heart problems in people with immune-related diseases like rheumatoid arthritis and lupus to help catch and treat these issues earlier.

  Recruiting University of Manchester · Manchester, Greater Manchester · NCT06600737

• UK CARDIO-IMID registry for heart disease in people with immune-mediated inflammatory conditions

  This registry will see if routine blood heart markers can predict future heart problems in people with immune-mediated inflammatory diseases.

  Recruiting at 2 sites University of Manchester · Edinburgh, Scotland and 1 other locations · NCT06478277

• Testing a new diet for managing bile acid diarrhoea

  This study is testing a new diet called The 8x5 Diet to see if it can help adults with bile acid diarrhoea manage their symptoms better than their usual diet.

  Recruiting University of Manchester · Manchester, Greater Manchester · NCT06259396

• Understanding how HIV treatment affects gut bacteria

  This study is trying to see how different HIV treatments affect gut bacteria in people living with HIV by looking at their stool samples before and after they change medications.

  Recruiting University of Manchester · Manchester, Greater Manchester · NCT06100211

• Exploring ICU patients' experiences and end-of-life wishes

  This study is trying to understand how patients in intensive care feel about their treatment and what their wishes are for end-of-life care to help improve future ICU experiences.

  Recruiting University of Manchester · Manchester · NCT06027684

• Identifying factors to prevent early stillbirths

  This study is trying to find out what changes can be made in behavior and healthcare to help prevent stillbirths that happen between 20 and 28 weeks of pregnancy.

  Recruiting University of Manchester · Manchester · NCT06005272

• Developing blood tests for predicting complications in stem cell transplantation

  This study is testing new blood tests to see if they can help predict complications like graft-versus-host disease and leukemia relapse in patients receiving stem cell transplants.

  Recruiting at 3 sites University of Manchester · Manchester and 2 other locations · NCT05567289

• Investigating immune changes in cancer patients undergoing radiotherapy

  This study looks at how radiotherapy changes the immune system in cancer patients by collecting blood and tissue samples before and after treatment.

  Recruiting University of Manchester · Manchester · NCT05076500

• Evaluating changes in MR imaging and biological parameters during radiotherapy for cancer

  This study is testing how tumors and healthy tissues change during cancer treatment with advanced MRI technology and weekly blood and urine samples from patients receiving standard care.

  Recruiting University of Manchester · Manchester · NCT04903236

• Specialized care for parents after stillbirth or neonatal death

  This study is testing a special care program for parents who have experienced stillbirth or neonatal death to see if it helps reduce anxiety and improve their next pregnancy outcomes.

  Recruiting University of Manchester · Manchester, Greater Manchester · NCT04393259

• Effects of Radiotherapy and Chemotherapy on Hearing in Head and Neck Cancer Patients

  This study is trying to see how treatments for head and neck cancer, like radiotherapy and chemotherapy, affect hearing in patients and which parts of the ear are most at risk of damage.

  Recruiting University of Manchester · Manchester · NCT03914378

NIH-funded research (2)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Using nasal drug delivery to improve treatment for neurological disorders

  This study is looking at a new way to help medicines delivered through the nose reach the brain better, which could be really helpful for people with tough brain conditions, making sure these medicines are safe and work well for them.

  NIH research University of Manchester · Manchester, United Kingdom · NIH-10701846

• Understanding how skin proteins affect drug absorption and metabolism

  This study is looking at how certain proteins in your skin help move and break down medications applied to the skin, with the hope of creating better treatments that are personalized for you without needing lots of expensive tests.

  NIH research University of Manchester · Manchester, United Kingdom · NIH-10670680

Quick answers

How many clinical trials run by University of Manchester are recruiting right now?

22, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 3 countries. The most sites are in United Kingdom (22 trials), Italy (1 trial), Spain (1 trial). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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