Clinical trial Recruiting at 1 site Interventional Ages 16 and up

Culturally adapted CBT for psychosis in Black people in the UK

Official title: Culturally-adapted Cognitive-behavioural Therapy for Black Sub-Saharan African and Caribbean People Experiencing Psychosis: A Case Series

Run by University of Manchester · NCT07252206 · Data updated 2026-11-12

A small series tests whether culturally tailored cognitive-behavioral therapy for psychosis is doable, acceptable, and safe for Black Sub-Saharan African and Caribbean individuals in the UK.

More Psychosis trials

Quick facts

Study typeInterventional
Ages16 Years and up
SexAll
Enrollment6 (estimated)
SponsorUniversity of Manchester
Academic / other
Locations1 site (Manchester)
StatusRecruiting
StartedFebruary 24, 2026
Main results expectedDecember 2026
Study endsDecember 2026
Registry record updatedJuly 10, 2026
Trial IDNCT07252206 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are Black British, Black Caribbean, Black African, or mixed African/Caribbean individuals with a schizophrenia-spectrum disorder who speak sufficient English and can participate in up to 16 CBT sessions.

Probably not a fit

Individuals with active substance use disorder, organic causes of psychosis, inability to consent, or current acute crisis may not benefit from this feasibility study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This case series evaluates the feasibility of culturally adapted CBT for psychosis among Black British, Caribbean, and African-descended individuals with psychosis or schizophrenia-spectrum disorders. Participants complete questionnaires, take part in up to 16 therapy sessions, and repeat measures to see changes, followed by a semi-structured interview about their therapy experience. The study focuses on practicality, acceptability, and safety rather than efficacy, and is conducted within the Greater Manchester area. The lead sponsor is the University of Manchester, in collaboration with the Greater Manchester Mental Health NHS Foundation Trust.

Why it matters

Potential benefit: If feasible and acceptable, the approach could lead to more accessible, culturally sensitive care for Black communities experiencing psychosis.

How similar studies have gone: Previous work suggests culturally tailored therapies can be feasible and acceptable in diverse populations, but data on psychosis-focused CBT for Black communities remain limited and exploratory.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Service users who identify as Black British, Black Caribbean, Black African, African-Caribbean or Mixed African/Caribbean with at least one parent and/or grandparent born in a Sub-Saharan African or Caribbean country
* People with a current ICD-10 schizophrenia spectrum disorder diagnosis, or who are currently receiving or have received support from an Early Intervention in Psychosis team
* 16 years or older
* Sufficient understanding of English to complete study measures and engage with CBTp

Exclusion Criteria:

* Current, primary diagnosis of substance use disorder
* Organic aetiology of psychosis
* Lacking capacity to provide full informed consent
* Currently experiencing a mental health crisis (i.e., are open to a home-based treatment team; are currently under Section of the Mental Health Act or have been under Section in the past 3 months) or immediate high risk to self or others (i.e., current suicidal intent or plans; unmanaged and intense non-suicidal self-injury)
* Currently receiving CBTp or received CBTp within the preceding 3 months
* Unwilling to participate in culturally-adapted CBTp

Where it's running

  • Greater Manchester Mental Health NHS Foundation Trust
    Manchester, United Kingdom
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.