Sponsor or institution
Clinical trials and research at Translational Genomics Research Inst
As of November 12, 2026, Find a Trial lists 30 NIH-funded research projects at this institution, with $44.5 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 30NIH research projects
NIH-funded research (30)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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CLU's role in Alzheimer's disease pathogenesis
Researchers are studying how the CLU gene may drive brain changes in Alzheimer's disease and how targeting CLU could lead to safer treatments.
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How glioblastoma changes across the tumor and over time during treatment
This work maps how glioblastoma tumors shift their cell types and interactions during and after treatment to find weaknesses that could help people with recurrent GBM.
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Understanding how early changes in lungs lead to progressive fibrotic disease
This grant studies the cells and genes involved in starting and advancing pulmonary fibrosis to uncover why some people progress to severe disease.
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Integrative Analysis Core for Longevity and Dementia Research
A broad, shared analysis resource aims to bring together multiple studies on aging, longevity, and Alzheimer’s disease to better understand how genetics and other factors influence healthy aging.
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Understanding Why Some People Age Well Despite Alzheimer’s and Related Dementias
Researchers are building patient-derived cell models to study why some people resist or slow down dementia and how aging affects brain cells, with a focus on Alzheimer’s Disease and related disorders.
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Drugs that slow aging and extend healthy years
A research project aims to find and test medicines that could slow aging and help people stay healthier longer.
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Extreme longevity and brain health in centenarians and families
This grant studies why some people live to 100 with strong thinking skills and how genes and biomarkers relate to Alzheimer’s disease and related dementias, aiming to help others stay cognitively healthy as they age.
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Longevity Factors: How biomarkers, genes, and environment relate to aging and healthy years
A large NIH project is studying how biology, genes, and environment help predict healthy aging and longevity in diverse populations.
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Longevity Consortium Administrative Core supports national aging research collaboration
A central Administrative Core coordinates and communicates about a large aging research collaboration and helps share data and results with scientists and the public.
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Longevity Consortium exploring aging and brain diseases with big data and diverse studies
A national program brings together many researchers to study aging, longevity, and Alzheimer’s-related conditions using diverse data sources and cross-study insights.
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High-resolution virome-wide infection analysis in type 1 diabetes birth cohorts
Researchers will study viruses over time in babies and young children to understand how infections may relate to developing type 1 diabetes.
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Small blood particle signals and fatty liver in children and teens
Researchers are looking at whether molecules carried in tiny blood particles can explain or signal fatty liver disease in children and adolescents with excess weight.
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Protein analysis to learn about aging and Alzheimer's disease
This project uses detailed protein measurements from people to find biological signs linked to aging, longevity, and Alzheimer's disease.
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Clearing harmful aging-like (senescent) cells to help treat pancreatic cancer
Researchers are trying an antibody that removes senescent cells to see if it helps chemotherapy and immunotherapy work better for people with pancreatic cancer.
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Discovering immune responses to tuberculosis in high disease burden populations
This study is looking at how our immune system responds to tuberculosis by exploring specific parts of the immune cells in people from areas where the disease is common, especially in sub-Saharan Africa, to find out what might help protect against it.
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Cell models for brain aging and dementia resilience
Researchers are making nerve cells from people’s blood and skin—including healthy adults, those with mild cognitive impairment or Alzheimer’s, and unusually long-lived individuals—to learn how some brains resist dementia.
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Finding drugs that slow aging and extend healthy life
This project looks for medicines that may slow aging and help adults stay healthier longer.
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Why some people reach 100 with strong memory and less dementia
This project looks at genes and blood-based markers in centenarians and their children to learn why some people live past 100 with good thinking and lower Alzheimer's risk.
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Why different species, including humans, age at different rates
This project looks across many animals to find genetic and molecular clues that might help people live healthier, longer lives.
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Biological markers linked to human lifespan and healthy aging
This project uses large health and biological databases to find which genes, proteins, and blood measures best predict how long and how healthily people live.
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Helping people age healthier and lower Alzheimer's risk
Teams combine decades of human data, lab tests, and animal work to find markers and targets that could help people live longer and reduce Alzheimer's risk.
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Identifying drugs that may help extend human lifespan
This study is looking for ways to help people age more slowly and stay healthier longer by finding new drug targets and understanding the biology of aging, which could lead to better treatments for age-related diseases.
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How genetic differences affect individual cells
This project looks at how people's genetic differences change activity inside individual cells to help link genes to disease.
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Targeting aging cells to improve treatment for pancreatic cancer
This study is looking at how getting rid of certain old cells in the body might help make pancreatic cancer treatments work better, and it’s inviting patients to join trials to see if this new method is safe and effective.
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Detailed viral exposure testing in children at risk for type 1 diabetes
This project uses a new blood-based test to look for past viral infections in children from type 1 diabetes birth cohorts to find links between viruses and later diabetes.
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Finding new diagnostic targets for a fungal infection called coccidioidomycosis.
This study is looking at how your body's antibodies respond to coccidioidomycosis, a fungal infection common in the southwestern U.S., to find new ways to improve tests that diagnose the infection more quickly and accurately.
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Examining the role of tiny vesicles in obesity and type 2 diabetes
This study is looking at tiny particles in the blood that come from our cells to see how they might play a role in obesity and type 2 diabetes, helping us understand how these conditions are connected and how weight loss or surgery can improve health.
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Analyzing genetic variations at the single cell level
This study is looking at how differences in our genes can change how our cells work and contribute to diseases, so that patients can get better, more personalized treatments based on their unique genetic makeup.
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Investigating RNA changes in blood for Parkinson's disease
This study is looking at how tiny pieces of RNA in blood can help us learn more about Parkinson's disease, with the goal of finding new ways to track the disease and improve treatments for patients like you.
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Using integrated approaches to develop therapies for healthy aging
This study is looking for ways to help people age healthier by finding signs in our bodies that are linked to living longer, and it's for anyone interested in how we can prevent diseases as we get older.
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