Finding new diagnostic targets for a fungal infection called coccidioidomycosis.
Official title: Proteome-wide Discovery of Diagnostic Targets for Coccidioidomycosis
Funded at Translational Genomics Research Inst · NIH-10989903 · Data updated 2026-11-12
This study is looking at how your body's antibodies respond to coccidioidomycosis, a fungal infection common in the southwestern U.S., to find new ways to improve tests that diagnose the infection more quickly and accurately.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Translational Genomics Research Inst NIH-funded |
| Lab location | 1 site (Phoenix, United States) |
| Project start | December 1, 2023 |
| Project end | October 31, 2025 |
| Funding year | 2025 |
| Award (this year) | $216,965 |
| NIH project number | 5R21AI180987-02 |
| Project ID | NIH-10989903 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with coccidioidomycosis or those experiencing symptoms related to this fungal infection.
✕Less likely to help
Patients who do not have coccidioidomycosis or related symptoms are unlikely to benefit from this research.
What this research studies
This research investigates the role of antibodies in coccidioidomycosis, a fungal infection prevalent in the southwestern United States. It aims to discover new protein targets within the Coccidioides fungus that could improve diagnostic tests. By analyzing B cells from patients, the researchers will identify novel antibodies that may help in understanding the disease better and developing faster diagnostic methods. The study employs advanced technologies to explore the immune response to this infection.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and rapid diagnostic tests for coccidioidomycosis, improving patient outcomes.
How similar studies have gone: Previous research has shown promise in identifying antibody roles in other fungal infections, suggesting that this approach may yield valuable insights.
Where this research is happening
-
Translational Genomics Research Inst
Phoenix, United States Active
Researchers
- Principal investigator: Mead, Heather Lynn — Translational Genomics Research Inst
- Study coordinator: Mead, Heather Lynn
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.