Investigating RNA changes in blood for Parkinson's disease
Official title: A Large-scale Extracellular Vesicle RNA-seq Resource for Parkinsons Disease
Funded at Translational Genomics Research Inst · NIH-10706937 · Data updated 2026-11-12
This study is looking at how tiny pieces of RNA in blood can help us learn more about Parkinson's disease, with the goal of finding new ways to track the disease and improve treatments for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Translational Genomics Research Inst NIH-funded |
| Lab location | 1 site (Phoenix, United States) |
| Project start | June 1, 2023 |
| Project end | May 31, 2026 |
| Funding year | 2023 |
| Award (this year) | $2,250,030 |
| NIH project number | 1R24NS132738-01 |
| Project ID | NIH-10706937 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with Parkinson's disease who are willing to participate in longitudinal sample collection.
✕Less likely to help
Patients without a diagnosis of Parkinson's disease or those who are not able to provide blood samples may not benefit from this research.
What this research studies
This research focuses on understanding how RNA found in extracellular vesicles from blood can provide insights into Parkinson's disease (PD). By collecting and analyzing samples from patients over time, the team aims to identify specific RNA changes that could serve as biomarkers for disease progression and treatment response. The study utilizes advanced techniques to isolate and characterize these RNA molecules, which may help in developing new therapies and improving patient care. Patients with PD will be closely monitored to gather extensive data that can benefit the broader research community.
Why it matters
Potential benefit: If successful, this research could lead to the discovery of new biomarkers that improve diagnosis and treatment strategies for Parkinson's disease.
How similar studies have gone: Other research has shown promise in using extracellular RNA as biomarkers in neurological diseases, indicating a potential for success in this approach.
Where this research is happening
-
Translational Genomics Research Inst
Phoenix, United States Active
Researchers
- Principal investigator: Craig, David W — Translational Genomics Research Inst
- Study coordinator: Craig, David W
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.