Finding drugs that slow aging and extend healthy life
Official title: Drug Targeting, Testing, and Development
Funded at Translational Genomics Research Inst · NIH-11195712 · Data updated 2026-11-12
This project looks for medicines that may slow aging and help adults stay healthier longer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Translational Genomics Research Inst NIH-funded |
| Lab location | 1 site (Phoenix, United States) |
| Project start | September 30, 2004 |
| Project end | August 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $1,353,502 |
| NIH project number | 5U19AG023122-17 |
| Project ID | NIH-11195712 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are adults (often middle-aged or older) willing to provide blood or tissue samples and possibly participate in early human trials.
✕Less likely to help
People under 21, those unwilling to give samples or undergo biopsies, and individuals seeking immediate treatment for a specific disease are unlikely to benefit directly.
What this research studies
The team uses computer chemistry tools to pick drug candidates and likely targets linked to aging. Promising drugs are tested in mice using molecular "Aging Rate Indicators" measured in blood, fat, muscle, liver, and brain to see if they slow age-related changes. The project also includes early, exploratory work in humans and pet dogs and draws on public data to guide choices. If you join, researchers may ask for blood samples, biopsies, or other tissue samples depending on the part of the project.
Why it matters
Potential benefit: If successful, this work could lead to medicines that delay age-related decline and increase healthy years of life.
How similar studies have gone: Related laboratory and mouse studies have found aging markers and some drugs that slow aging in animals, but human testing remains early and limited.
Where this research is happening
-
Translational Genomics Research Inst
Phoenix, United States Active
Researchers
- Principal investigator: Miller, Richard a — Translational Genomics Research Inst
- Study coordinator: Miller, Richard a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.