Longevity Factors: How biomarkers, genes, and environment relate to aging and healthy years
Official title: Human Longevity Associations, Trajectories and Predictions
Funded at Translational Genomics Research Inst · NIH-11399384 · Data updated 2026-11-12
A large NIH project is studying how biology, genes, and environment help predict healthy aging and longevity in diverse populations.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Translational Genomics Research Inst NIH-funded |
| Lab location | 1 site (Phoenix, United States) |
| Project start | September 30, 2004 |
| Project end | August 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $994,962 |
| NIH project number | 5U19AG023122-18 |
| Project ID | NIH-11399384 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals across diverse ages and backgrounds whose health data and samples are included in the consortium, particularly those with aging-related health concerns.
✕Less likely to help
Participants outside the included populations or with conditions not addressed by the biomarker analyses may see limited direct benefit.
What this research studies
This grant supports a big data effort to understand how biomarkers from blood, genetics, and other measures predict aging outcomes across different groups. Researchers will harmonize existing data, add new genomic and health information, and use advanced statistics and machine learning to find context-specific patterns. The goal is to clarify how sex, diversity, and environment affect the links between biology and aging, with an eye toward improving healthspan. Collaborations with multiple projects will integrate findings into a broader aging framework.
Why it matters
Potential benefit: If successful, patients could benefit from better risk prediction for age-related conditions and personalized approaches to maintain health as they age.
How similar studies have gone: Previous aging biomarker studies show promising associations, but this project emphasizes context and diversity to strengthen applicability.
Where this research is happening
-
Translational Genomics Research Inst
Phoenix, United States Active
Researchers
- Principal investigator: Lapidus, Jodi a — Translational Genomics Research Inst
- Study coordinator: Lapidus, Jodi a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.