Sponsor or institution
Clinical trials and research at Louisiana State Univ Hsc Shreveport
As of November 12, 2026, Find a Trial lists 106 NIH-funded research projects at this institution, with $50.6 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 106NIH research projects
NIH-funded research (newest 40 of 106)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Targeting endothelial NOX1 to protect brain blood vessels in Alzheimer's disease
This project tests whether blocking NOX1 in brain blood vessel cells can prevent blood flow problems and brain damage in Alzheimer's disease.
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Metabolic syndrome and brain support cells: how it may lead to Alzheimer’s disease
A researcher is studying how midlife metabolic problems like diabetes and obesity may disrupt brain cells that support neurons, potentially leading to Alzheimer's disease and related dementia in later life.
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Spatio-temporal regulation of neutrophil behavior in the lungs during acute injury
Researchers are studying how immune cells in the lungs change shape and behavior during acute lung injury to understand why some responses help fight infection and others cause damage.
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Understanding how CDH1 loss drives aggressive stomach cancer and how to target it
Researchers are studying why certain advanced stomach cancers grow and spread, with a focus on CDH1 inactivation and related pathways to find ways to improve treatment for patients.
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Lymph vessel channels (Piezo1 and TRPV4) and weight gain
Looking at how two channels in lymph vessels (Piezo1 and TRPV4) may cause lymph leakage and contribute to weight gain in adults with obesity.
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Regulation of vascular muscle cell identity by TEADs in adult arteries
A study to understand how TEAD family proteins help keep vascular smooth muscle cells in their healthy, contractile state in adult arteries and how this may relate to a dangerous artery condition.
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Cellular redox balance and the cleanup of inflamed arteries
A study in people is not involved yet, but the grant explores how boosting antioxidant balance could help the body clear dead cells in arteries and reduce inflammation tied to atherosclerosis.
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New approaches to protect the heart after pneumococcal pneumonia
Aims to find ways to prevent heart damage and later heart problems in adults hospitalized with pneumonia caused by Streptococcus pneumoniae.
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What controls scarring in diseased hearts
Testing a new drug that blocks a protein called GSK-3α to try to reduce heart scarring in adults with heart failure.
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Modeling ALS Pathology with Patient-Derived Neuromuscular Organoids
A study using patient-derived stem cells to grow 3D neuromuscular organoids that mimic ALS-affected connections between nerves and muscles.
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Role of PD-L1 in heart disease after injury and cancer
Researchers are studying how a protein called PD-L1 in heart cells affects heart injury and cancer treatment, with the aim of making heart damage from therapy safer.
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How lung cells help TB fight or fail the infection
A research project is studying how alveolar cells in the lungs respond to tuberculosis to uncover new ways to protect lung tissue and reduce damage.
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New kinase targets to protect the heart from injury
Researchers are studying heart kinases to find new ways to prevent or treat heart damage after a heart attack.
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Neutrophil integrin α9 and blood clots after stroke in aging
This project looks at how a molecule on white blood cells called neutrophil integrin α9 might cause dangerous vein clots after a stroke, especially in older adults.
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Nutrient signals help macrophages clear dead cells to calm inflammation in artery disease
This grant explores how macrophages eat dead cells in arteries and how that process could slow or stabilize dangerous artery plaques in ASCVD.
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Clearance of Dead Liver Cells by Immune Cells in NASH
Researchers are studying how liver macrophages remove dead liver cells in NASH to uncover new ways to treat the disease.
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How a heart protein (HIPK2) affects scarring and function after a heart attack
The team is looking at how a protein called HIPK2 influences heart scarring and weakening after a heart attack in adults with heart disease.
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Lipin-1 helps macrophages resolve inflammation in atherosclerosis
This grant explores how Lipin-1 helps immune cells resolve inflammation in artery disease to reduce heart risk.
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Understanding how arterial baroreceptors influence high blood pressure
A research project is exploring whether nerves that sense blood pressure in the arteries help drive drug-resistant high blood pressure, using mouse models to study this neural pathway.
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Redox, Environment, and Metabolomics links to heart health in people with substance use
A study using blood samples and health data to explore how certain chemicals in the blood relate to heart disease risk, especially in people who use substances.
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Understanding why some patients have heart damage from doxorubicin and how to predict it
This grant looks at why doxorubicin can damage the heart in some patients and how genetic differences, especially related to oxidative stress, might help predict who is at higher risk.
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CSE and hydrogen sulfide: new clues about aging and blood vessels
A doctor-scientist at LSU Health Shreveport is studying how a molecule called CSE and hydrogen sulfide affect aging blood vessels and heart-related health.
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Redox signaling core for heart disease research
A core facility at Louisiana State University Shreveport helps researchers study how redox biology affects cardiovascular diseases.
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Animal Models and Histology Core for cardiovascular research
A core facility at LSU Shreveport helps researchers study blood vessels, heart disease, and related biology by providing tissue processing, staining, genotyping, and imaging services to support cardiovascular research.
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Administrative Core of a cardiovascular redox biology and disease training program
A national program at Louisiana State University Shreveport aims to grow junior researchers in redox biology and cardiovascular disease through mentorship, training, and shared facilities.
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Center for Redox Biology and Cardiovascular Disease
A large, long-running program at LSU Health Shreveport is exploring how redox biology affects heart and blood vessel diseases to improve prevention and treatment for patients in Louisiana and beyond.
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MEIS1’s role in vascular disease and changing artery cells
This grant explores how MEIS1 controls vascular smooth muscle cell behavior in arteries affected by atherosclerosis and restenosis.
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Light alcohol use and stroke care: could small amounts help brain blood vessels
A study explores whether very light alcohol consumption could help people at risk for ischemic stroke by promoting brain blood vessel growth and healing.
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Understanding How Body Chemistry, Environment, and Metabolism Affect Disease
This work explores how changes in our body's chemistry, our surroundings, and how our body uses energy might lead to various health conditions.
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How liver immune cells clear dead liver cells in NASH
This project looks at how liver macrophages remove dying liver cells in people with NASH to find targets for new treatments.
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How COVID-19 Infection Might Accelerate Lewy Pathology and Dementia
This NIH grant explores how COVID-19 could influence brain changes linked to dementia, focusing on people affected by Alzheimer's disease and related dementias.
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Eosinophils and Bordetella infections: how these immune cells help bacteria persist and spread
This grant studies how eosinophils influence persistent Bordetella infections, which can cause whooping cough, and what that means for preventing spread and improving treatments.
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How EphA2 controls artery plaque behavior and stability
A study in people at risk for artery disease looks at how a specific cell signal (EphA2) influences inflammation and plaque stability in arteries.
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Tracking CMV-fighting NK cells in salivary glands
A study to understand how specialized natural killer cells in salivary glands help control CMV infection in people with AIDS or weakened immunity.
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How the body's filters affect severe arbovirus infections (EEEV)
Aims to understand how the body clears the virus and how this affects spread, using a model of Eastern equine encephalitis virus to improve future treatments.
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A safer lab system to study how bunyaviruses enter cells and trigger antibodies
A new, safer lab approach (BSL2) to study how bunyaviruses get into cells and how our immune system recognizes them, with potential implications for vaccines and therapies.
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Immunophenotyping Core for Advanced Immunology and Inflammation
A national program is expanding expert immunophenotyping tools to help scientists study immune responses and inflammation, while training junior researchers at LSU Health Shreveport.
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Bioinformatics and Modeling Core for Immunology and Disease Modeling
A COBRE center at LSU Health Shreveport is building a Bioinformatics and Modeling Core to help understand immune system roles in diseases and train junior researchers.
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Immunology and Disease Pathways Core for junior researchers
A centralized program supports early-career scientists to study how immune system problems contribute to disease and translation to potential treatments.
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Center for Applied Immunology and Pathological Processes (CAIPP) at LSU Health Shreveport
A multi-year program in Louisiana aims to deepen understanding of how immune responses work in health and disease to help prevent and treat infections, cancer, and inflammatory conditions.
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