How the body's filters affect severe arbovirus infections (EEEV)
Official title: Project 3-Defining cellular mediators of viremia control and heparan sulfate binding specificity in arbovirus infection.
Funded at Louisiana State Univ Hsc Shreveport · NIH-11336499 · Data updated 2026-11-12
Aims to understand how the body clears the virus and how this affects spread, using a model of Eastern equine encephalitis virus to improve future treatments.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Louisiana State Univ Hsc Shreveport NIH-funded |
| Lab location | 1 site (Shreveport, United States) |
| Project start | March 1, 2021 |
| Project end | February 28, 2031 |
| Funding year | 2026 |
| Award (this year) | $221,250 |
| NIH project number | 2P20GM134974-06A1 |
| Project ID | NIH-11336499 on NIH RePORTER |
Who could benefit from this research
✓Could help
Not applicable to current patients; findings may inform future therapies for people at risk of arboviral infections.
✕Less likely to help
No direct patient participation in this specific project.
What this research studies
This project looks at how the virus interacts with the body’s surface sugars and which immune cells clear circulating virus. Using a safe virus model in mice and advanced lab techniques, researchers will map which cells and tissues are responsible for removing the virus from blood. Findings could reveal new targets to prevent viral spread and severe disease in people exposed to arboviruses like EEEV.
Why it matters
Potential benefit: Knowledge from this work could guide the development of therapies that limit viral spread and reduce severe outcomes in humans exposed to dangerous arboviruses.
How similar studies have gone: Other studies using HS-binding patterns have advanced understanding of viral clearance, though this project focuses on EEEV-specific mechanisms in a mouse model.
Where this research is happening
-
Louisiana State Univ Hsc Shreveport
Shreveport, United States Active
Researchers
- Principal investigator: Ander, Stephanie — Louisiana State Univ Hsc Shreveport
- Study coordinator: Ander, Stephanie
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.