Sponsor or institution
Clinical trials and research at Jesse Brown VA Medical Center
As of November 12, 2026, Find a Trial lists 69 NIH-funded research projects at this institution. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 69NIH research projects
NIH-funded research (newest 40 of 69)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
-
New ways to stop rheumatoid arthritis damage and relieve pain
Researchers are testing novel targets to prevent the problematic tissue growth in rheumatoid arthritis so people, including veterans, can move more freely and feel better.
-
SHAPE: a wearable shoulder-and-hand device to help after stroke
This project will build and try a wearable device that supports the shoulder and helps move the hand for people with long-standing arm problems after a stroke.
-
SHAPE: a shoulder-and-hand wearable to help people with long-term arm weakness after stroke
This project is building and trying out a wearable device that supports the shoulder and powers the hand to help people with chronic arm weakness after stroke.
-
Prosthetic foot and ankle stiffness for above-knee amputees' walking and standing
This project changes stiffness in prosthetic feet and ankles to find settings that help people with above-knee amputations walk and stand better without making their prosthetic knee unstable.
-
Helping Veterans speak up and make shared decisions about their diabetes care
This project offers a brief video-based program to help Veterans with type 2 diabetes communicate better with their doctors and stick to treatment plans.
-
Do Powered Knee Prostheses Improve Mobility for Transfemoral Amputees
A new powered knee prosthesis with motor-assisted bending and straightening is being tested to see if it improves walking for people who have lost a leg above the knee.
-
In situ bioprinting for bone regeneration to repair craniofacial injuries in military personnel
A new 3D bioprinting approach uses cell-filled microgels to directly repair damaged craniofacial bone in soldiers and Veterans.
-
Multi-tissue 3D-printed trachea for airway repair
A patient-facing overview of a project that uses advanced 3D bioprinting to create a functional trachea from patient cells to help people with severe airway damage.
-
Targeted Sleep Apnea Treatment with Dronabinol Instead of a generic pill
A study in veterans tests whether the FDA-approved drug dronabinol can reduce sleep apnea severity and who is most likely to benefit.
-
How a gut protein (P-glycoprotein) affects inflammatory bowel disease
This work looks at whether problems with a gut protein called P‑glycoprotein contribute to ulcerative colitis and Crohn's disease and how that changes gut bacteria.
-
Understanding how ankle-foot stiffness affects comfort in prosthetic limbs
This study is looking at how the stiffness of prosthetic ankle-foot devices affects comfort for Veterans who have had a leg amputated below the knee, and it aims to make these devices more comfortable and better suited to each person's needs by gathering their feedback.
-
Does a smart knee prosthesis improve mobility and life quality for veterans with above-knee amputation
A microprocessor-controlled knee could help veterans with above-knee amputations move more easily and feel better about daily life.
-
Military toxic exposures and their effects on brain health and thinking
Looking at whether past military-related arsenic exposures are linked to low brain DHA and to mood, anxiety, or memory problems in veterans, and whether raising DHA could help protect the brain.
-
Gut microbes and diarrhea risk in Gulf War veterans
This project looks at whether changes in gut microbes explain why Gulf War and other deployed veterans get frequent diarrhea and related gut problems.
-
How a natural protein (MFG-E8) may help the liver heal after cell loss
This work looks at whether the protein MFG-E8 helps the liver recover after liver-cell death, which could help people with acute or chronic liver injury.
-
Why some ovarian cancers resist platinum chemotherapy: changes in tumor metabolism
This project looks at how ovarian tumors change their metabolism when they stop responding to platinum chemotherapy and seeks new targets and markers to help women with recurrent high-grade serous ovarian cancer.
-
How the gut controls bile acids and cholesterol
Researchers are learning how a gut protein that recycles bile acids influences blood cholesterol in people at risk for heart disease.
-
Targeted nanotherapy for precision cancer care in veterans
This project tests a nanoparticle treatment that targets cholesterol-hungry, treatment-resistant cancers in veterans.
-
How the gut protein DRA helps repair the bowel lining
Researchers are looking at whether the protein DRA helps the intestines heal better in people with Crohn’s disease or ulcerative colitis.
-
Leveraging glucagon to treat diabetes mellitus
A new approach aims to use glucagon in a controlled way to improve diabetes by targeting a liver pathway that helps the body manage glucose and insulin.
-
Targeting pancreatic cancer by interrupting nerve-growth signals and cancer cell survival pathways
A new approach aims to slow pancreatic cancer by blocking signals from nerves that feed tumors and by hitting key cancer-supporting pathways, which could make standard treatments more effective for patients with pancreatic cancer.
-
Investigating cholesterol management in veterans with diabetes and cardiovascular disease risk
This study is looking at new ways to help veterans with diabetes and heart issues lower their bad cholesterol levels by understanding how their gut affects cholesterol, so they can stay healthier.
-
Speeding myelin repair with lanthionine ketimine derivatives
This project tests whether lanthionine ketimine–based compounds can help people with multiple sclerosis regrow the protective myelin around their nerves.
-
MNK signaling's effect on the immune attack in pancreatic cancer
The team is exploring whether blocking MNK enzymes can help immune cells enter and better fight pancreatic cancer tumors in people with pancreatic ductal adenocarcinoma.
-
Liver protein complex that drives inflammation and gut damage in alcohol-related liver disease
This project looks at how a protein released from the liver sparks inflammation that harms both the liver and the gut in people with alcohol-related liver disease.
-
Stopping harmful joint tissue growth in rheumatoid arthritis
A new treatment approach aims to block the growth of inflamed joint tissue (pannus) in people with rheumatoid arthritis who do not respond to current medicines.
-
A safer asparaginase treatment for liver (hepatocellular) cancer
A human-like, less-toxic form of the cancer drug asparaginase is being developed for adults with hepatocellular (liver) cancer whose tumors need the amino acid asparagine.
-
Understanding how acute myeloid leukemia becomes resistant to treatment
This research explores why acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) sometimes get worse or stop responding to treatment, focusing on how the body's immune response and certain genetic changes play a role.
-
Enhancing Veterans’ Post-COVID Mobility with a Cognitive-Sensorimotor Gait Framework
A study to understand why some veterans have persistent gait and balance problems after COVID-19 and how cognitive and sensory factors contribute to mobility issues.
-
Understanding how alcohol use disorder affects the brain and behavior
This study is looking at how drinking alcohol affects the brain and its connection to anxiety, especially in veterans, to help find better ways to support people dealing with alcohol use and anxiety issues.
-
Investigating how hormones affect the development of liver disease
This study is looking at how hormones like estrogen and growth hormone affect liver health, especially in women after menopause who are more likely to develop a liver condition called NASH, and it hopes to find new ways to prevent or treat this disease.
-
Investigating a peptide to promote remyelination in multiple sclerosis
This study is exploring a new treatment for people with multiple sclerosis that uses a special nasal spray to help repair the protective covering of nerve fibers, with the hope of improving nerve function and easing symptoms.
-
Investigating how tumor cells affect immune cells in lung cancer
This study is looking at how certain immune cells in lung cancer are affected by a substance made by tumors, with the goal of finding new ways to improve cancer treatments that help your immune system fight the disease.
-
Creating 3D-printed bioinks for regenerating bone tissue
This study is exploring a new way to help military personnel and veterans heal from bone injuries in their face by using 3D printing to create special gels filled with stem cells that can be placed directly into the body to help grow new bone tissue.
-
Creating a new trachea using advanced 3D printing techniques
This study is working on a new way to create trachea tissue for veterans and soldiers with serious airway damage, using 3D printing to build a replacement that works like natural tissue and helps them breathe better.
-
Helping Veterans communicate better during medical visits
This study is helping veterans with Type 2 diabetes learn how to talk more openly with their doctors during visits, using a helpful video, so they can make better choices about their health together.
-
Understanding and treating neurodegenerative diseases like Alzheimer's and Multiple Sclerosis.
This study is looking into what causes Alzheimer's and Multiple Sclerosis and how we can use already approved medications to help treat these conditions, with the hope of making life better for those living with these diseases.
-
Evaluating the Ossur Power Knee for improved mobility in amputees
This study is looking at how the Ossur Power Knee, a special powered prosthetic knee, can help people with leg amputations walk better and move more easily in their daily lives.
-
Investigating cancer mechanisms and potential treatments for pancreatic and breast cancer
This study is looking at how certain changes in our cells can lead to pancreatic and breast cancer, and it's working on creating new treatments that can help control these changes to fight the cancer better.
-
Investigating how AMPK and CD36 affect the spread of breast cancer
This study is looking at how certain proteins in the body can affect the spread of breast cancer, especially when someone is on a high-fat diet, and it hopes to find new ways to help patients by targeting these proteins.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.