Understanding and treating neurodegenerative diseases like Alzheimer's and Multiple Sclerosis.
Official title: BLR&D Research Career Scientist Award Application
Funded at Jesse Brown VA Medical Center · NIH-11052885 · Data updated 2026-11-12
This study is looking into what causes Alzheimer's and Multiple Sclerosis and how we can use already approved medications to help treat these conditions, with the hope of making life better for those living with these diseases.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Jesse Brown VA Medical Center NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | October 1, 2019 |
| Project end | September 30, 2031 |
| Funding year | 2025 |
| NIH project number | 2IK6BX004852-06 |
| Project ID | NIH-11052885 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or Multiple Sclerosis, particularly those who may benefit from new therapeutic approaches.
✕Less likely to help
Patients with neurodegenerative diseases not related to Alzheimer's or Multiple Sclerosis may not receive direct benefits from this research.
What this research studies
This research focuses on identifying the causes of neurodegenerative diseases, particularly Alzheimer's and Multiple Sclerosis (MS), and developing effective treatments. The approach includes repurposing existing FDA-approved drugs that show promise in animal models, which can expedite their availability for clinical use. The research also investigates the role of specific brain cells, such as oligodendrocytes and astrocytes, in disease progression and recovery. By understanding how these diseases evolve and identifying potential interventions, the goal is to alleviate symptoms and improve the quality of life for affected individuals.
Why it matters
Potential benefit: If successful, this research could lead to new treatment options that significantly improve the management of neurodegenerative diseases.
How similar studies have gone: Previous research has shown promise in repurposing drugs for neurodegenerative diseases, indicating potential for success in this area.
Where this research is happening
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Jesse Brown VA Medical Center
Chicago, United States Active
Researchers
- Principal investigator: Feinstein, Douglas L. — Jesse Brown VA Medical Center
- Study coordinator: Feinstein, Douglas L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.