Investigating cancer mechanisms and potential treatments for pancreatic and breast cancer
Official title: BLR&D Research Career Scientist Award Application
Funded at Jesse Brown VA Medical Center · NIH-11050910 · Data updated 2026-11-12
This study is looking at how certain changes in our cells can lead to pancreatic and breast cancer, and it's working on creating new treatments that can help control these changes to fight the cancer better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Jesse Brown VA Medical Center NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | October 1, 2019 |
| Project end | September 30, 2029 |
| Funding year | 2025 |
| NIH project number | 2IK6BX004855-06 |
| Project ID | NIH-11050910 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with pancreatic or breast cancer, particularly those with Triple Negative breast cancer.
✕Less likely to help
Patients with cancers unrelated to pancreatic or breast cancer may not receive any benefit from this research.
What this research studies
This research focuses on understanding the molecular mechanisms that lead to pancreatic and breast cancer. The team is exploring how certain cellular pathways become dysregulated, resulting in uncontrolled cell growth. They aim to develop small molecules that can target these dysregulated proteins to help mitigate the effects of these cancers. The research includes studying specific protein kinases and their inhibitors, which have shown promise in preclinical models.
Why it matters
Potential benefit: If successful, this research could lead to new targeted therapies for pancreatic and breast cancer, potentially improving patient outcomes.
How similar studies have gone: Previous research has shown success in targeting similar pathways in cancer treatment, indicating a promising avenue for this approach.
Where this research is happening
-
Jesse Brown VA Medical Center
Chicago, United States Active
Researchers
- Principal investigator: Rana, Ajay Nmn — Jesse Brown VA Medical Center
- Study coordinator: Rana, Ajay Nmn
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.