Investigating cancer mechanisms and potential treatments for pancreatic and breast cancer
BLR&D Research Career Scientist Award Application
This study is looking at how certain changes in our cells can lead to pancreatic and breast cancer, and it's working on creating new treatments that can help control these changes to fight the cancer better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Jesse Brown VA Medical Center NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-11050910 on NIH RePORTER |
What this research studies
This research focuses on understanding the molecular mechanisms that lead to pancreatic and breast cancer. The team is exploring how certain cellular pathways become dysregulated, resulting in uncontrolled cell growth. They aim to develop small molecules that can target these dysregulated proteins to help mitigate the effects of these cancers. The research includes studying specific protein kinases and their inhibitors, which have shown promise in preclinical models.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with pancreatic or breast cancer, particularly those with Triple Negative breast cancer.
Not a fit: Patients with cancers unrelated to pancreatic or breast cancer may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new targeted therapies for pancreatic and breast cancer, potentially improving patient outcomes.
How similar studies have performed: Previous research has shown success in targeting similar pathways in cancer treatment, indicating a promising avenue for this approach.
Where this research is happening
Chicago, United States
- Jesse Brown VA Medical Center — Chicago, United States (Active)
Researchers
- Principal investigator: Rana, Ajay Nmn — Jesse Brown VA Medical Center
- Study coordinator: Rana, Ajay Nmn
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.