Understanding how alcohol use disorder affects the brain and behavior
Official title: BLRD Research Career Scientist Award Application
Funded at Jesse Brown VA Medical Center · NIH-11105863 · Data updated 2026-11-12
This study is looking at how drinking alcohol affects the brain and its connection to anxiety, especially in veterans, to help find better ways to support people dealing with alcohol use and anxiety issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Jesse Brown VA Medical Center NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | April 1, 2022 |
| Project end | March 31, 2029 |
| Funding year | 2025 |
| NIH project number | 5IK6BX006030-04 |
| Project ID | NIH-11105863 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include veterans and individuals experiencing alcohol use disorder, particularly those with anxiety symptoms.
✕Less likely to help
Patients who do not have alcohol use disorder or related anxiety issues may not benefit from this research.
What this research studies
This research investigates the biological mechanisms behind alcohol use disorder (AUD) and its relationship with anxiety disorders, particularly in veterans. The study focuses on how alcohol exposure alters gene expression in the brain, specifically in areas related to anxiety and addiction. By examining both animal models and human brain samples, the research aims to uncover the epigenetic changes that occur due to alcohol use and withdrawal. This could lead to better understanding and treatment options for those struggling with AUD and anxiety.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for individuals suffering from alcohol use disorder and co-occurring anxiety disorders.
How similar studies have gone: Previous research has shown promising results in understanding the biological mechanisms of alcohol use disorder, indicating that this approach has potential for success.
Where this research is happening
-
Jesse Brown VA Medical Center
Chicago, United States Active
Researchers
- Principal investigator: Pandey, Subhash C. — Jesse Brown VA Medical Center
- Study coordinator: Pandey, Subhash C.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.