Sponsor or institution
Clinical trials and research at Henry Ford Health + Michigan State University Health Sciences
As of November 12, 2026, Find a Trial lists 174 NIH-funded research projects at this institution, with $136.4 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 174NIH research projects
NIH-funded research (newest 40 of 174)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Keloid recurrence study using multi-omics in diverse patients
A research effort will look at why keloids come back after surgery, especially in African American patients, using comprehensive molecular data from patient samples.
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A national program to build a precise, personalized health data platform for all of us participants
This grant supports expanding and improving a national health data platform to help tailor care to each person using their genetic, health, and lifestyle information.
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Computational modeling of female hormone balance and drug responses
A new computational model uses patient-like data to predict how metabolic drugs will work in women across their hormonal cycles and different reproductive stages.
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Anti-CD38 immunotherapy for severe hidradenitis suppurativa
A new treatment using anti-CD38 therapy is being tested for people with severe hidradenitis suppurativa who have not responded to prior therapies.
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Vitamin D, gut bacteria and dementia risk in older adults with HIV
This work will look at whether low vitamin D and changes in gut bacteria are linked to higher dementia risk in older adults living with chronic HIV and similar community members.
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Screening new compounds to reverse gene signatures in IPF lungs
A researcher hopes to find compounds that reverse harmful gene changes in the lungs of people with idiopathic pulmonary fibrosis (IPF).
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VIP Interneurons and Brain Circuits in Tuberous Sclerosis
A study to understand how loss of a brain gene (Tsc1) affects VIP interneurons and the frontal brain region in people and models with Tuberous Sclerosis Complex.
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Parenting support for Congolese mothers to help children's mental health
This follows children of Congolese mothers who did or did not get a year-long parenting program to learn whether early parent support links to better mental health at school age.
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Using zinc sparks to predict embryo quality in assisted reproduction
This project looks at a tiny zinc signal released by eggs at fertilization to predict which embryos are most likely to grow well in IVF.
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Assay tools and biomarkers for polyamine-related cancers
A national team is developing tests and biomarkers to understand how polyamine-related gene changes drive certain cancers and neurodevelopmental disorders, with patient samples helping build better diagnostics.
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Natural history study of rare polyamine disorders in children and adults
A patient-friendly study is tracking how polyaminopathies progress over time to better understand their health and daily challenges.
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Career-Enhancing Training to Develop Therapies for Rare Genetic Disorders
A grant to nurture scientists who will create new ways to treat rare genetic diseases and train the next generation of clinicians and researchers.
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Pilot Feasibility Governance Core drives biomarker discovery and patient-oriented rare-disease research
A pilot-feasibility core supports biomarker discovery and improved diagnosis for polyamine-related disorders by connecting patients, families, clinicians, and researchers.
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Administrative Core for the Center for Polyamine Disorders
A centralized Administrative Core helps manage a national research network focused on polyamine disorders, guiding funding, policies, data use, and patient-facing information.
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Center for Polyamine Disorders group study of rare metabolic disorders
A research consortium is studying a group of rare metabolic disorders linked to polyamines and aims to understand symptoms, biomarkers, and disease progression to improve care.
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Urban living and infant brain development: a gut-brain link
A short study in infants will explore how growing up in cities might shape brain development and gut microbes, which could influence later mental health.
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How our own cells fight intracellular bacterial infections without antibiotics
A study to understand how human immune cells inside our bodies can naturally block bacteria like Legionella from growing, with the goal of helping design therapies that boost this internal defense.
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Fibroblast-made GABA fuels PDAC immune suppression
In people with pancreatic cancer, this study explores how a specific cell type in the tumor environment uses a brain-like chemical (GABA) to dampen immune attack against the cancer.
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Deep phenotyping to map osteoarthritis progression
A study will combine symptoms, joint structure, and daily activity data to identify patterns that predict osteoarthritis progression and potential biomarkers.
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Digital alcohol-reduction aid for young cancer survivors
A technology-based program helps adolescents and young adults who have survived cancer reduce risky drinking in a way that fits with the challenges of post-treatment life.
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Re-imagining e-SBIRT to reduce stigma and strengthen FASD prevention
A new approach uses digital support to help pregnant people reduce alcohol use and prevent FASD, aiming to fit into routine prenatal care.
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Dimensional Complexity as a Brain Biomarker for Resilience in Aging and Dementia
A biomarker from resting-state brain scans may help predict which people are likely to stay cognitively healthy as they age.
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A strengths-based curriculum for Tribal early childhood education to support lifelong health and wellness
A culturally grounded program helps preschool-aged Indigenous children learn traditional foods, language, movement, and wellbeing in tribal education settings.
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Transcriptomic changes in endometriosis development (early lesions)
This grant studies how gene activity changes in early endometriotic lesions, aiming to understand better why endometriosis develops and how it might be detected earlier.
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Receptor Cd74 links inflammation to alcohol-related liver disease
Aims to understand how a specific immune signal called CD74, working with MIF, contributes to liver damage from alcohol and what that could mean for new treatments.
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Training program to reduce pregnancy-related and pregnancy-associated morbidity and mortality disparities
A multi-year training program helps scientists and trainees build skills to study and reduce disparities in pregnancy-related health outcomes.
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Community Partnership Consortium focusing on maternal health disparities
A community-driven effort partners with families, community organizations, health systems, and policymakers to guide maternal health research and turn findings into real changes.
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Scale-up approach to reduce pregnancy-related harm and disparities
A national-scale plan to spread proven hospital and community care practices to reduce pregnancy-related harm and disparities, especially in outpatient and community settings.
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PRAMM: a patient-friendly digital program to reduce pregnancy-related morbidity
A digital program called PC-PRAMM uses a flexible app to screen pregnant people, share tailored guidance, and connect them to live help to reduce pregnancy-related complications.
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Multilevel, community-centered plan to reduce pregnancy-related illness and death and close disparities
A large, real-world trial will test a coordinated set of community and healthcare changes to reduce pregnancy complications and death, with a focus on Black, Hispanic, and Medicaid populations.
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Multilevel Approaches to Improve Maternal Health in Black Communities
A large U.S. program tests community-partnered strategies across health systems to reduce pregnancy-related illness and death and close racial disparities in maternal health.
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Whole-genome sequencing to understand hidradenitis suppurativa in diverse groups
Researchers will study the genetic factors that contribute to hidradenitis suppurativa, especially in African American, Hispanic/Latino, and White patients, to better understand why some people are more affected.
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Adaptive psychological support to reduce opioid use after injury
A flexible, patient-friendly program helps adults recovering from an injury use fewer opioids by offering a brief online education and mindfulness activity, followed by more in-depth sessions if needed.
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UTS-1401: a potential medicine to reduce harm from radiation exposure
A new drug candidate, UTS-1401, is being tested in animals to see if it can lessen blood-forming tissue damage after radiation exposure.
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Integrated care to improve outcomes after early liver transplant for alcohol-associated liver disease
A multi-center study will pair liver transplant care with behavioral and biopsychosocial support to help people with alcohol-related liver disease who are considered for early transplant.
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Pregnancy and postpartum harms from overdoses, self-harm, and violence
This project looks at how drug overdoses, suicide attempts, and assaults affect people during pregnancy and the first year after birth across multiple U.S. states.
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Gut-borne particles and PTSD after brain injury
A doctor-research team is studying how tiny gut-borne vesicles might influence PTSD and anxiety after a brain injury, with findings that could lead to new ways to help patients.
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Why ERK helps KRAS-driven pancreatic cancer grow
This project looks at how a cell signaling protein called ERK helps KRAS-mutant pancreatic tumors grow, aiming to find new ways to stop them for people with pancreatic cancer.
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Improving PrEP use in primary care for HIV prevention
A project tests different ways to increase new PrEP prescriptions in primary care clinics to help prevent HIV among people who could benefit.
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Repurposing Vonoprazan as an inhaled therapy for IPF
A high-profile NIH grant is testing whether an existing drug, vonoprazan, can be inhaled to slow or reverse lung fibrosis in people with idiopathic pulmonary fibrosis (IPF).
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