Keloid recurrence study using multi-omics in diverse patients
Official title: A multi-omic investigation of keloid disease recurrence
Funded at Henry Ford Health + Michigan State University Health Sciences · NIH-11641647 · Data updated 2026-11-12
A research effort will look at why keloids come back after surgery, especially in African American patients, using comprehensive molecular data from patient samples.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Henry Ford Health + Michigan State University Health Sciences NIH-funded |
| Lab location | 1 site (East Lansing, United States) |
| Project start | September 21, 2026 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $300,000 |
| NIH project number | 1R56AR087418-01 |
| Project ID | NIH-11641647 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals with keloid disease, especially African American patients who experience higher recurrence rates after surgery.
✕Less likely to help
People without keloids or those not undergoing surgical treatment may not directly benefit.
What this research studies
Keloid disease causes painful, itchy scars that can recur after surgery. This grant uses multi-omics to study why some scars return, with a focus on diverse patient populations included in the U.S. It plans to examine cellular makeup and molecular signals from keloid tissues to identify factors linked to recurrence. Participants may contribute tissue samples and clinical information, enabling better prediction and future treatments. The study aims to build a more complete picture of why recurrence happens and how to prevent it.
Why it matters
Potential benefit: If successful, the research could lead to personalized strategies to prevent keloid recurrence after surgery.
How similar studies have gone: Previous work suggests cellular heterogeneity plays a role, but single-cell data in diverse populations are limited, making this study relatively novel.
Where this research is happening
-
Henry Ford Health + Michigan State University Health Sciences
East Lansing, United States Active
Researchers
- Principal investigator: Jones, Lamont — Henry Ford Health + Michigan State University Health Sciences
- Study coordinator: Jones, Lamont
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.