Improving PrEP use in primary care for HIV prevention
Official title: A Multilevel, Multiphase Optimization Strategy for PrEP: Patients and Providers in Primary Care
Funded at Henry Ford Health + Michigan State University Health Sciences · NIH-11371435 · Data updated 2026-11-12
A project tests different ways to increase new PrEP prescriptions in primary care clinics to help prevent HIV among people who could benefit.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Henry Ford Health + Michigan State University Health Sciences NIH-funded |
| Lab location | 1 site (East Lansing, United States) |
| Project start | September 22, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2026 |
| Award (this year) | $739,809 |
| NIH project number | 5R01MD018523-04 |
| Project ID | NIH-11371435 on NIH RePORTER |
Who could benefit from this research
✓Could help
Primary care providers and patients who meet PrEP indications at Henry Ford Health System and participating clinics.
✕Less likely to help
Some patients may not benefit if their risk profile changes or if PrEP is not appropriate for them.
What this research studies
This project uses a structured optimization approach to test multiple components that could help clinicians offer PrEP more consistently in primary care. It will gather feedback from both providers and patients to understand context and barriers. The study will run an optimization trial across multiple clinics, followed by interviews to understand what helped or hindered implementation.
Why it matters
Potential benefit: If successful, the work could lead to higher PrEP prescribing rates in primary care, reducing HIV risk in underserved populations.
How similar studies have gone: Previous studies show structured implementation approaches can improve preventive care uptake, with this project applying a novel optimization framework to PrEP delivery.
Where this research is happening
-
Henry Ford Health + Michigan State University Health Sciences
East Lansing, United States Active
Researchers
- Principal investigator: Lockhart, Elizabeth — Henry Ford Health + Michigan State University Health Sciences
- Study coordinator: Lockhart, Elizabeth
Related research
Other NIH-funded projects on the same topics.
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Improving HIV prevention for adolescents through better pediatric care
This study is all about helping doctors who care for kids and young adults learn how to better talk about and prescribe a medicine called PrEP, which can help prevent HIV, so that more young people can stay healthy and safe.
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Helping women learn about PrEP during primary care visits
A tech-based program in primary care will help women at higher risk for HIV, especially those with low health literacy, understand and choose PrEP for prevention.
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Improving PrEP Access for HIV Prevention in Primary Care
This project aims to find the best ways for primary care doctors to offer HIV prevention medication (PrEP) to more patients, especially those who currently receive it less often.
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Helping women learn about HIV prevention options
This study is all about helping women, especially those at higher risk for HIV, learn more about a preventive medication called PrEP during their regular doctor visits, so they can make informed choices about their health and feel comfortable discussing it with their healthcare providers.
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HEARTS hypertension and diabetes care in Guatemala
This grant tests how well the HEARTS primary care model works in Guatemala to improve blood pressure and blood sugar control for patients.
-
mChoice: Boosting PrEP Use and Adherence for Black and Latino MSM with Tailored Training and Support
A national study to help Black and Latino men who have sex with men start and stick with PrEP through culturally matched provider training and patient support.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.