NIH-funded research NIH-funded research

Pregnancy and postpartum harms from overdoses, self-harm, and violence

Official title: Pregnancy-associated mortality and morbidity due to drugs, self-harm, and violence in the United States

Funded at Henry Ford Health + Michigan State University Health Sciences · NIH-11385681 · Data updated 2026-11-12

This project looks at how drug overdoses, suicide attempts, and assaults affect people during pregnancy and the first year after birth across multiple U.S. states.

More Pregnancy research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionHenry Ford Health + Michigan State University Health Sciences
NIH-funded
Lab location1 site (East Lansing, United States)
Project startSeptember 30, 2021
Project endAugust 31, 2027
Funding year2025
Award (this year)$500,000
NIH project number2R56HD102319-05
Project IDNIH-11385681 on NIH RePORTER

Who could benefit from this research

Could help

The focus is on people who are pregnant or within one year after delivery, especially those with substance use, mental-health crises, or exposure to violence, and who live or receive care in the states included in the project.

Less likely to help

People who are not pregnant or postpartum, who live outside the U.S., or whose health issues are unrelated to overdose, self-harm, or violence are unlikely to benefit directly from this research.

What this research studies

The team will track deaths and nonfatal events (drug overdoses, suicidal behavior, and assaults) that occur during pregnancy and the first postpartum year across several U.S. states. Researchers will analyze state vital records, hospital and emergency department data, and other large datasets to count events and map trends over time and by geography and individual characteristics. They will compare multi-state findings to previous California results and examine how area-level factors like healthcare availability relate to these harms. The goal is to pinpoint high-risk populations and places where prevention and services could be strengthened.

Why it matters

Potential benefit: If successful, the work could help direct prevention programs and healthcare resources to reduce overdoses, self-harm, and violence affecting pregnant and postpartum people.

How similar studies have gone: Previous work by the team in California found far more nonfatal overdoses, suicide attempts, and assaults than deaths during pregnancy and postpartum, but comparable multi-state data are still limited.

Where this research is happening

  • Henry Ford Health + Michigan State University Health Sciences
    East Lansing, United States
    Active

Researchers

  • Principal investigator: Margerison, Claire E — Henry Ford Health + Michigan State University Health Sciences
  • Study coordinator: Margerison, Claire E

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.