Multilevel, community-centered plan to reduce pregnancy-related illness and death and close disparities
Official title: Multilevel community-centered intervention to reduce pregnancy related and associated morbidity and mortality (PRAMM) and disparities
Funded at Henry Ford Health + Michigan State University Health Sciences · NIH-11408524 · Data updated 2026-11-12
A large, real-world trial will test a coordinated set of community and healthcare changes to reduce pregnancy complications and death, with a focus on Black, Hispanic, and Medicaid populations.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Henry Ford Health + Michigan State University Health Sciences NIH-funded |
| Lab location | 1 site (East Lansing, United States) |
| Project start | August 17, 2023 |
| Project end | July 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $959,568 |
| NIH project number | 5U54HD113291-04 |
| Project ID | NIH-11408524 on NIH RePORTER |
Who could benefit from this research
✓Could help
Pregnant individuals or those planning pregnancy in participating communities, particularly Medicaid beneficiaries and racial/ethnic groups disproportionately affected by disparities.
✕Less likely to help
Individuals outside the participating regions or those not matched to the study’s inclusion criteria may not experience direct benefit.
What this research studies
This project tests a practical, multilevel approach in real clinics and communities to improve maternal health. It strengthens community health worker–driven home visiting, with added pre- and postnatal focus on maternal health and targeted CHW actions to address disparities. It also trains providers on better communication, cultural relevance, and connecting patients to community resources. The effort leverages existing state systems to broaden reach and impact across multiple counties.
Why it matters
Potential benefit: If successful, the program could lower pregnancy-related morbidity and mortality and reduce disparities for pregnant people, especially those who are Medicaid beneficiaries or identify as Black or Hispanic.
How similar studies have gone: Prior community- and provider-focused maternal health interventions have shown promise in improving care and outcomes, though results vary by setting and implementation.
Where this research is happening
-
Henry Ford Health + Michigan State University Health Sciences
East Lansing, United States Active
Researchers
- Principal investigator: Meghea, Cristian Ioan — Henry Ford Health + Michigan State University Health Sciences
- Study coordinator: Meghea, Cristian Ioan
Related research
Other NIH-funded projects on the same topics.
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Training program to reduce pregnancy-related and pregnancy-associated morbidity and mortality disparities
A multi-year training program helps scientists and trainees build skills to study and reduce disparities in pregnancy-related health outcomes.
-
Scale-up approach to reduce pregnancy-related harm and disparities
A national-scale plan to spread proven hospital and community care practices to reduce pregnancy-related harm and disparities, especially in outpatient and community settings.
-
PRAMM: a patient-friendly digital program to reduce pregnancy-related morbidity
A digital program called PC-PRAMM uses a flexible app to screen pregnant people, share tailored guidance, and connect them to live help to reduce pregnancy-related complications.
-
Pregnancy and Heart Health: Predicting and Preventing Pregnancy-Related Cardiovascular Problems
A research grant is developing advanced data tools to identify pregnant women at high risk of heart-related complications so clinicians can prevent maternal death.
-
Expanding hospital and community care to reduce pregnancy-related illness, deaths, and racial gaps
This project is rolling out proven care bundles in hospitals and community clinics to help pregnant and postpartum people—especially Black birthing people—have fewer serious health problems and deaths.
-
Pregnancy Checkup app to lower pregnancy-related illness and deaths
This expands a pregnancy app to give pregnant people tailored risk screening, helpful content, and immediate live-chat support to connect them with services.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.