Coordination and data sharing for ARDS, pneumonia, and sepsis research
Official title: Coordination for ARDS, Pneumonia, and Sepsis supporting Training, Organization and Network Efficiency (CAPSTONE)
Funded at Vanderbilt University Medical Center · NIH-11325818 · Data updated 2026-11-12
A national collaborative effort to improve how researchers study ARDS, pneumonia, and sepsis by coordinating centers, data collection, and analyses.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project start | May 1, 2023 |
| Project end | April 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $6,710,197 |
| NIH project number | 5U01HL168478-04 |
| Project ID | NIH-11325818 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients with acute respiratory distress, pneumonia, or sepsis at participating clinical centers who contribute data and samples as part of the APS Phenotyping Consortium.
✕Less likely to help
Patients not enrolled in the APS Phenotyping Consortium or those not connected to participating centers may not directly benefit.
What this research studies
This grant funds a coordinating center that will harmonize data collection across clinical sites, support researchers with training and organization, and help scientists discover insights about ARDS and related conditions. The team will implement a standardized data platform, manage multi-modal measurements, and help identify distinct patient subgroups with similar prognosis or response to treatment. By providing centralized analytics, protocol support, and data sharing, it aims to accelerate discoveries that could improve patient care. The effort focuses on advancing mechanistic understanding of critical illness and recovery through robust collaboration.
Why it matters
Potential benefit: If successful, patients with ARDS and related conditions could benefit from faster translation of research findings into better treatments and care plans.
How similar studies have gone: Previous coordinated research efforts have shown that standardized data collection and collaboration can accelerate breakthroughs in critical illness.
Where this research is happening
-
Vanderbilt University Medical Center
Nashville, United States Active
Researchers
- Principal investigator: Self, Wesley H — Vanderbilt University Medical Center
- Study coordinator: Self, Wesley H
Related research
Other NIH-funded projects on the same topics.
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Coordinating ARDS, Pneumonia, and Sepsis research to improve care
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Understanding ARDS, pneumonia, and sepsis: a big study to map how illness and recovery unfold
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This study is looking at the differences in the biology of people with Acute Respiratory Distress Syndrome (ARDS), pneumonia, and sepsis to better understand how these conditions affect recovery, and it's inviting 1,000 participants from California to help by sharing their health information and samples over the next y
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Improving care for patients with ARDS, pneumonia, and sepsis
This study is all about improving care for people with serious lung issues like ARDS, pneumonia, and sepsis by gathering and analyzing data from a diverse group of patients, so we can better understand these conditions and find the best treatments for everyone.
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Understanding the recovery patterns of patients with ARDS, pneumonia, and sepsis
This study is looking for people who have had serious breathing problems, like ARDS, pneumonia, or sepsis, to learn more about their recovery and find ways to better predict and improve their health outcomes.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.