Coordinating ARDS, Pneumonia, and Sepsis research to improve care
Official title: Coordination for ARDS, Pneumonia, and Sepsis supporting Training, Organization and Network Efficiency (CAPSTONE)
Funded at Vanderbilt University Medical Center · NIH-11595454 · Data updated 2026-11-12
A national coordinating center helps researchers studying ARDS and related infections work together more efficiently to learn what helps patients recover.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project start | May 1, 2023 |
| Project end | April 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $109,092 |
| NIH project number | 3U01HL168478-04S1 |
| Project ID | NIH-11595454 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with ARDS, pneumonia, or sepsis who are enrolled in the APS Phenotyping Consortium and associated clinical centers.
✕Less likely to help
Patients not enrolled in the APS Phenotyping Consortium or not receiving care at participating centers may not directly benefit.
What this research studies
This grant funds a collaborative hub across Vanderbilt, Johns Hopkins, and UCSF to streamline data collection, analysis, and collaboration for ARDS, pneumonia, and sepsis research. It supports standardized, multi-modal data capture and secure data sharing to identify patient phenotypes and mechanisms of illness. The center helps clinical sites enroll diverse patients, manage studies, and accelerate findings that could improve prognosis and treatments for critically ill adults.
Why it matters
Potential benefit: If successful, patients with ARDS and related infections could benefit from faster, more precise insights leading to better treatments and recovery.
How similar studies have gone: Prior multi-site consortia with standardized data capture have shown improved research quality and faster discovery, though this exact coordination model is being established in this program.
Where this research is happening
-
Vanderbilt University Medical Center
Nashville, United States Active
Researchers
- Principal investigator: Self, Wesley H — Vanderbilt University Medical Center
- Study coordinator: Self, Wesley H
Related research
Other NIH-funded projects on the same topics.
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Understanding ARDS, pneumonia, and sepsis: a big study to map how illness and recovery unfold
A large patient study at the University of Pennsylvania will follow adults with ARDS, pneumonia, or sepsis to learn how these conditions progress and recover over time.
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Coordination and data sharing for ARDS, pneumonia, and sepsis research
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Molecular profiling of ARDS, pneumonia, and sepsis in adults using advanced sequencing
A research team at four California hospitals will study adults with ARDS, pneumonia, or sepsis to identify molecular patterns in their illness using genetic sequencing.
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Investigating the molecular characteristics of ARDS, pneumonia, and sepsis
This study is looking at the differences in the biology of people with Acute Respiratory Distress Syndrome (ARDS), pneumonia, and sepsis to better understand how these conditions affect recovery, and it's inviting 1,000 participants from California to help by sharing their health information and samples over the next y
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Improving care for patients with ARDS, pneumonia, and sepsis
This study is all about improving care for people with serious lung issues like ARDS, pneumonia, and sepsis by gathering and analyzing data from a diverse group of patients, so we can better understand these conditions and find the best treatments for everyone.
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Understanding the recovery patterns of patients with ARDS, pneumonia, and sepsis
This study is looking for people who have had serious breathing problems, like ARDS, pneumonia, or sepsis, to learn more about their recovery and find ways to better predict and improve their health outcomes.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.