Condition

Thyroid Eye Disease clinical trials and research

• 10Clinical trials
• 3NIH research projects
• 6Countries

Newest Thyroid Eye Disease clinical trials

All recruiting trials (10)

• Imaging Comparison of 68Ga-FAPI and 68Ga-DOTATATE in Thyroid Eye Disease

  This study tests two PET imaging methods (FAPI and DOTATATE) to see which best images activity in the eyes of adults with thyroid eye disease.

  Recruiting Daping Hospital and the Research Institute of Surgery of the Third Military Medical University · Chongqing, Chongqing Municipality · NCT07835607

• IBI3031 in Thyroid Eye Disease (TED)

  A first-in-human test in adults with moderate-to-severe TED to see if IBI3031 is safe and tolerable when given by shot under the skin or into a vein.

  Recruiting Phase 1 Innovent Biologics (Suzhou) Co. Ltd. · Shenyang, Liaoning · NCT07622368

• AMG 732 for thyroid eye disease in a rollover, open-label study

  This study tests AMG 732 in adults with moderate-to-severe thyroid eye disease who previously did not respond or relapsed, to see if the treatment helps symptoms and is safe over a rollover period.

  Recruiting at 8 sites Phase 2 Amgen · Little Rock, Arkansas and 7 other locations · NCT07438405

• Teprotumumab N01 for adults with thyroid eye disease

  This will try Teprotumumab N01 in adults with recent-onset thyroid eye disease to see if it reduces eye inflammation and improves vision and quality of life.

  Recruiting Peking University Third Hospital · Beijing · NCT07423013

• Teprotumumab N01 vs IV steroids for active thyroid eye disease

  This trial tests whether teprotumumab N01 can help people with active thyroid eye disease better than intravenous steroids.

  Recruiting Phase 4 Innovent Biologics (Suzhou) Co. Ltd. · Shanghai, Shanghai Municipality · NCT07265258

• Testing IBI311 for inactive thyroid eye disease.

  This trial will test whether IBI311 improves eye signs and symptoms and is safe for people with inactive thyroid eye disease.

  Recruiting Phase 3 Innovent Biologics (Suzhou) Co. Ltd. · Shenyang, Liaoning · NCT07113262

• Evaluating a new imaging method for Thyroid Eye Disease

  This study is testing a new imaging method to see if it can better assess the activity of Thyroid Eye Disease compared to the traditional imaging technique for patients with this condition.

  Recruiting Peking University Third Hospital · Beijing, Beijing Municipality · NCT06359795

• Teprotumumab for treating thyroid eye disease and thyroid dysfunction

  This study is testing how well teprotumumab can help people with thyroid eye disease who have serious symptoms like bulging eyes, pain, and double vision.

  Recruiting Walter Reed National Military Medical Center · Bethesda, Maryland · NCT06275373

• Evaluating linsitinib for thyroid eye disease

  This study is testing if a new drug called linsitinib can help people with moderate to severe thyroid eye disease who haven't improved with other treatments.

  Recruiting at 2 sites Phase 2/3 Sling Therapeutics, Inc. · Miami, Florida and 1 other locations · NCT06112340

• Evaluating how high doses of prednisolone affect patients with inflammatory conditions

  This study is trying to see how different doses of prednisolone affect patients with inflammatory conditions by looking at their blood levels and how their bodies process the medication.

  Recruiting Imperial College London · London · NCT05012033

NIH-funded research (3)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Why the soft tissues behind the eye overgrow in thyroid eye disease

  This research is looking at how immune signals make the cells behind the eye grow, turn into fat and scar tissue, and cause symptoms in people with thyroid eye disease.

  NIH research University of Rochester · Rochester, United States · NIH-11138621

• Understanding how IGF-1R affects thyroid eye disease

  This study is looking at how a specific protein called IGF-1R behaves in people with thyroid eye disease, which can affect vision and daily life, to help find new ways to treat the condition.

  NIH research University of California, San Diego · La Jolla, United States · NIH-10996866

• Understanding how immune responses affect eye tissue in thyroid eye disease

  This study is looking into how certain antibodies cause inflammation and changes in the eyes of people with thyroid eye disease, which can make their eyes bulge and affect their vision, and it aims to find better treatment options for those affected.

  NIH research University of Rochester · Rochester, United States · NIH-10900579

Related topics

Quick answers

How many Thyroid Eye Disease clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in China (6 trials), United States (3 trials), Poland (1 trial), Spain (1 trial), Taiwan (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1, Phase 1: 1, Phase 4: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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