Condition

Graves Ophthalmopathy clinical trials and research

• 9Clinical trials
• 1New in 30 days
• 5Countries

Newest Graves Ophthalmopathy clinical trials

All recruiting trials (9)

• ETHY-001 safety and activity in Thyroid Eye Disease (TED)

  This study tests ETHY-001 versus placebo to see if it is safe, tolerable, and shows activity in people with thyroid eye disease.

  Recruiting at 2 sites Phase 1 Ethyreal Bio, Inc. · Orland Park, Illinois and 2 other locations · NCT07885605

• AI-based MRI and ultrasound for thyroid-related eye disease

  This study tests an AI model using orbital MRI and eye ultrasound to help diagnose activity and severity of thyroid-associated ophthalmopathy and predict its course in adults.

  Recruiting Shanghai Changzheng Hospital · Shanghai, Huangpu District · NCT07716397

• Tofacitinib for steroid‑resistant moderate-to-severe thyroid eye disease

  This will test whether taking oral tofacitinib (5 mg twice daily) for 24 weeks can reduce eye bulging and inflammation in adults with moderate-to-severe thyroid eye disease who don't respond to or cannot take high-dose steroids.

  Recruiting Phase 2 The First Affiliated Hospital of Xiamen University · Xiamen, Fujian · NCT07547930

• Links between inflammation, thyroid antibodies, and retinal changes in Graves disease

  This study will see if blood markers of inflammation and thyroid antibodies are linked to retinal measurements from OCT in adults with Graves disease and in healthy adults.

  Recruiting Elazıg Fethi Sekin Sehir Hastanesi · Elâzığ, Elaziğ · NCT07480720

• Atorvastatin and vitamin D for active thyroid eye disease

  This trial tests whether taking atorvastatin and/or vitamin D with usual care can reduce eye inflammation and bulging in adults with active thyroid eye disease.

  Recruiting Taipei Veterans General Hospital, Taiwan · Taipei, Taiwan · NCT07400757

• Teprotumumab for treating thyroid eye disease and thyroid dysfunction

  This study is testing how well teprotumumab can help people with thyroid eye disease who have serious symptoms like bulging eyes, pain, and double vision.

  Recruiting Walter Reed National Military Medical Center · Bethesda, Maryland · NCT06275373

• Evaluating linsitinib for thyroid eye disease

  This study is testing if a new drug called linsitinib can help people with moderate to severe thyroid eye disease who haven't improved with other treatments.

  Recruiting at 2 sites Phase 2/3 Sling Therapeutics, Inc. · Miami, Florida and 1 other locations · NCT06112340

• Using Bimatoprost eye drops to treat Graves' Orbitopathy

  This study is testing if Bimatoprost eye drops can help reduce bulging eyes and other symptoms in people with Graves' disease.

  Recruiting Early Phase 1 Johns Hopkins University · Seattle, Washington · NCT03708627

• Treatment for Graves' ophthalmopathy using simvastatin

  This study is testing if simvastatin can help people with mild to moderate Graves' ophthalmopathy avoid getting worse.

  Recruiting Phase 3 Lund University · Malmö · NCT03131726

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Quick answers

How many Graves Ophthalmopathy clinical trials are recruiting right now?

9, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in United States (4 trials), China (2 trials), Turkey (Türkiye) (1 trial), Sweden (1 trial), Taiwan (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 1, Early Phase 1: 1, Phase 2/3: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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