Condition
Graves Orbitopathy clinical trials and research
As of November 12, 2026, Find a Trial lists 4 Graves Orbitopathy clinical trials that are recruiting, at sites in 3 countries (most in United States (2), Denmark (1), China (1)). By phase: Phase 3 (1), Phase 2/3 (1), Phase 2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 4Clinical trials
- 3Countries
Newest Graves Orbitopathy clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Early risk stratification of thyroid eye disease in newly diagnosed Graves' disease | — | Herlev | Recruiting | Sep 10, 2026 |
| Linsitinib in moderate to severe Thyroid Eye Disease (TED) | Phase 3 | Glendale, Arizona and 17 other locations | Recruiting | Aug 7, 2026 |
| Tofacitinib for steroid‑resistant moderate-to-severe thyroid eye disease | Phase 2 | Xiamen, Fujian | Recruiting | Apr 23, 2026 |
| Evaluating linsitinib for thyroid eye disease | Phase 2/3 | Miami, Florida and 1 other locations | Recruiting | Nov 1, 2023 |
All recruiting trials (4)
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Early risk stratification of thyroid eye disease in newly diagnosed Graves' disease
This study tests whether early eye-related signs, blood and tear biomarkers, or eye surface features can predict who with Graves’ disease will develop thyroid eye disease within a year.
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Linsitinib in moderate to severe Thyroid Eye Disease (TED)
This study tests whether linsitinib can help people with moderate to severe TED associated with Graves' disease or Hashimoto's thyroiditis.
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Tofacitinib for steroid‑resistant moderate-to-severe thyroid eye disease
This will test whether taking oral tofacitinib (5 mg twice daily) for 24 weeks can reduce eye bulging and inflammation in adults with moderate-to-severe thyroid eye disease who don't respond to or cannot take high-dose steroids.
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Evaluating linsitinib for thyroid eye disease
This study is testing if a new drug called linsitinib can help people with moderate to severe thyroid eye disease who haven't improved with other treatments.
Related topics
Quick answers
How many Graves Orbitopathy clinical trials are recruiting right now?
4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 3 countries. The most sites are in United States (2 trials), Denmark (1 trial), China (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 3: 1, Phase 2/3: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.