Condition

Spinal Fusion clinical trials and research

• 16Clinical trials
• 7NIH research projects
• 12Countries

Newest Spinal Fusion clinical trials

All recruiting trials (16)

• Blood Transfusion Factors and Cell Saver Use in Kids’ Spine Surgery

  This study looks at which factors put pediatric scoliosis patients at risk for needing donor blood during posterior spinal fusion and how using a Cell Saver during surgery might reduce that need.

  Recruiting Tunis University · Tunis · NCT07661589

• Ear (auricular) vagus nerve stimulation to lower inflammation after long spinal fusion

  This trial will test whether non-invasive ear-based vagus nerve stimulation can lower inflammation, improve blood sugar control, and reduce pain after long-segment spinal fusion surgery.

  Recruiting Washington University School of Medicine · St Louis, Missouri · NCT07218133

• Preoperative IV iron for teens having spinal fusion to correct scoliosis

  This trial will try giving a single IV iron infusion before spinal fusion to see if it helps 10–19-year-olds with scoliosis and low iron by reducing blood transfusions and improving recovery.

  Recruiting Phase 2/3 Columbia University · New York, New York · NCT07217873

• Evaluation of 3D Digital Surgery in Traumatology

  This study is testing if using 3D digital surgery tools can help patients with orthopedic conditions have better surgery outcomes and fewer complications compared to traditional methods.

  Recruiting Corporacion Parc Tauli · Sabadell, Barcelona · NCT06603831

• Liposomal bupivacaine versus standard bupivacaine with epinephrine for pain after adolescent spinal fusion

  This trial tests whether injecting liposomal bupivacaine instead of 0.25% bupivacaine with epinephrine during posterior spinal fusion reduces opioid use after surgery in adolescents aged 10 to 17 with idiopathic scoliosis.

  Recruiting Boston Children's Hospital · Boston, Massachusetts · NCT06471348

• Comparing two rod techniques for spinal fusion surgery

  This study is testing whether using a different type of rod in spinal fusion surgery can help prevent problems after the operation for people who have had back surgery.

  Recruiting at 13 sites AO Foundation, AO Spine · Redwood City, California and 16 other locations · NCT06368245

• Using Aprepitant to Prevent Nausea in Children After Scoliosis Surgery

  This study tests if a medication called Aprepitant can help reduce nausea and vomiting in children after they have surgery for scoliosis.

  Recruiting Phase 2 IWK Health Centre · Halifax, Nova Scotia · NCT06357234

• Using laser therapy to reduce lower back pain after spinal surgery

  This study is testing if a special laser therapy can help people with chronic lower back pain feel better after having spinal surgery.

  Recruiting at 2 sites University of California, Los Angeles · Los Angeles, California and 1 other locations · NCT06282770

• Modulating pulse-width during spinal surgery

  This study is testing how different settings of electrical stimulation during spinal surgery can affect the safety and effectiveness of the procedure for patients.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT06120231

• Observing endothelial damage during major spine surgery

  This study is trying to see if major spine surgery causes damage to blood vessel lining by checking blood samples from patients before and after their surgery.

  Recruiting Istituto Ortopedico Rizzoli · Bologna, BO · NCT06119542

• Iron supplementation for adolescents with scoliosis

  This study tests if giving iron supplements to teenagers with scoliosis before their surgery can help them recover better and need fewer blood transfusions.

  Recruiting Columbia University · New York, New York · NCT06042699

• Using nerve blocks to reduce pain and improve recovery in older adults after spinal surgery

  This study is testing if a special nerve block can help older adults feel less pain and recover better after spinal surgery.

  Recruiting Early Phase 1 University of Iowa · Iowa City, Iowa · NCT05461092

• Evaluating the safety and effectiveness of INFUSE Bone Graft for spinal fusion

  This study is testing how safe and effective the INFUSE Bone Graft is for spinal fusion surgery in patients in Korea over a year after their operation.

  Recruiting Medtronic Spinal and Biologics · Seoul · NCT05299762

• Fusion versus decompression alone for single-level lumbar stenosis

  This trial will test whether decompression surgery without added fusion works as well as decompression plus fusion for adults aged 45–75 with single-level lumbar spinal stenosis.

  Recruiting at 2 sites Sklifosovsky Institute of Emergency Care · Moscow, Moscow and 1 other locations · NCT05273879

• Registry for patients with personalized spine rods

  This study is testing whether personalized spine rods can help patients who have had spinal surgery feel better and have fewer problems compared to those with standard rods.

  Recruiting University of Colorado, Denver · Aurora, Colorado · NCT04601363

• Using vancomycin powder with bone graft to prevent infections after spine surgery

  This study is testing if using vancomycin powder with bone grafts can help prevent infections after spine surgery for patients who haven't found relief from other treatments.

  Recruiting Taipei Veterans General Hospital, Taiwan · Taipei · NCT03883022

NIH-funded research (7)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Wireless metacages that measure spine fusion progress in real time

  A tiny, wireless, self-powered cage grown into your spine could tell doctors how well your spinal fusion is progressing, without bulky hardware.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11412539

• Small molecule block of noggin to improve spinal fusion

  A promising approach to help spine fusion uses a tiny molecule to block noggin, allowing safer, lower doses of bone-building signals at the fusion site.

  NIH research Emory University · Atlanta, United States · NIH-11367538

• Flexible 3D‑printed spine cages to improve spinal fusion

  This project tests whether softer, 3D‑printed spinal cages help bone fuse faster and hold up better for adults who need interbody spinal fusion.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11259437

• A New Medicine to Help Spinal Bones Fuse

  This research explores a new way to help spinal bones grow together by using a special medicine to reduce side effects often seen with current bone-healing treatments.

  NIH research Emory University · Atlanta, United States · NIH-11163278

• Exploring how flexible spinal implants affect healing in the spine

  This study is looking at new flexible spinal implants to see how they help with healing after surgery, which could lead to better recovery for people with back problems.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11005400

• Blocking noggin to enhance spinal fusion

  This study is exploring a new way to help your spine heal better after surgery by using a special material that helps encourage bone growth while reducing side effects, and it's showing good results in early tests with rabbits.

  NIH research Emory University · Atlanta, United States · NIH-10847502

• Understanding opioid misuse in adolescents after spinal surgery

  This study is looking at how teens aged 12-18 handle pain after spinal fusion surgery and whether they might misuse opioids afterward, so we can find better ways to help them manage their pain safely.

  NIH research Seattle Children's Hospital · Seattle, United States · NIH-10264717

Related topics

Quick answers

How many Spinal Fusion clinical trials are recruiting right now?

16, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 12 countries. The most sites are in United States (9 trials), Spain (2 trials), Canada (2 trials), Taiwan (1 trial), South Korea (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2/3: 1, Phase 2: 1, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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