Condition
Serious Mental Illness clinical trials and research
As of November 12, 2026, Find a Trial lists 8 Serious Mental Illness clinical trials that are recruiting, at sites in 3 countries (most in United States (6), Botswana (1), Puerto Rico (1)). The most active sponsors are Massachusetts General Hospital (2), VA Office of Research and Development (2). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 8Clinical trials
- 3Countries
Newest Serious Mental Illness clinical trials
All recruiting trials (8)
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BRIDGE NET: virtual collaborative care for patients with serious mental illness and new cancer
A virtual, team-based care program tests whether BRIDGE NET can improve care for adults with serious mental illness who are newly diagnosed with cancer.
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Engaging Latinos with Serious Mental Illness Using Culturally Responsive Peer Support
This pilot tests whether culturally tailored, peer-delivered motivational interviewing can help Latinos with serious mental illness start or restart mental health care.
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Facilitating Tobacco Treatment in Veterans with Serious Mental Illness
This project tests an external facilitation approach to help VA clinics prescribe smoking medications more often to Veterans with serious mental illness who smoke.
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Changing Lives and Changing Outcomes-9 group program at Worcester Recovery Center and Hospital
This program will try a nine-session cognitive-behavioral group to help adults with serious mental illness who have current or past legal involvement increase mental health awareness and lower chances of future legal problems.
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A program to help older adults with serious mental illness improve social connections and healthy living.
This study is testing a new program to see if it can help older adults with serious mental illness build better social connections and live healthier lives.
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Bridges to Better Health and Wellness for Puerto Rico’s Serious Mental Illness
A culturally tailored program with monthly health care manager visits to help people with serious mental illness in Puerto Rico see if better primary care and reduced stigma can lower chronic disease risk.
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Improving rehabilitation for veterans with serious mental illness
This study is testing a new computer program to help veterans with serious mental illnesses improve their thinking and daily life skills.
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Reducing stigma to help women with serious mental illness and HIV in Botswana stay virally suppressed
We will test a stigma-reduction program for women in Botswana who have serious mental illness and HIV to help them stay on HIV treatment and keep their viral load low after leaving psychiatric hospital.
Related topics
Quick answers
How many Serious Mental Illness clinical trials are recruiting right now?
8, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 3 countries. The most sites are in United States (6 trials), Botswana (1 trial), Puerto Rico (1 trial). Each study page lists its sites and which ones are recruiting.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.