Improving rehabilitation for veterans with serious mental illness

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to enhance therapeutic interventions for veterans suffering from serious mental illnesses (SMI) by introducing Targeted Cognitive Training (TCT). TCT is a computerized program designed to improve sensory information processing, which can lead to better cognitive and psychosocial functioning. The study will utilize EEG biomarkers to identify veterans who are most likely to benefit from this treatment, ensuring a tailored approach to rehabilitation. By focusing on veterans receiving care in VA Psychosocial Rehabilitation and Recovery Centers, the study seeks to address the cognitive impairments that significantly impact their daily lives.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Veterans with SMI (e.g., schizophrenia, schizoaffective disorder, bipolar disorder, PTSD) being treated at PRRCs or co-located rehabilitative services.
* Age 18 and 83 years.
* Fluency in spoken and written English.
* Ability to detect 1000 Hz tones binaurally at a 40-dB sound pressure level.
* Ability to see with an acuity of 20/40 with both eyes tested together (corrected if applicable) by a standard printed Snellen eye chart reading card.

Exclusion Criteria:

* Estimated premorbid IQ below 70, as estimated via the WRAT-4 Reading subtest.
* Active substance use other than cannabis within the last 30 days as determined by CPRS review, self- report, or positive urine drug screen (obtained as part of the screening process).
* History of significant medical or neurological illness.
* Inability to comprehend or provide informed consent.

Where it's running

• VA San Diego Healthcare System, San Diego, CA
  San Diego, California, United States Recruiting

Study contacts

• Principal investigator: Gregory Light, PhD — VA San Diego Healthcare System, San Diego, CA
• Study coordinator: Joyce Sprock, BS
• Email: joyce.sprock@va.gov
• Phone: (858) 552-8585

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.