BRIDGE NET: virtual collaborative care for patients with serious mental illness and new cancer
Official title: Improving Care Delivery for Individuals With Mental Illness and Cancer Across a Cancer Center Network: A Randomized Trial
Run by Massachusetts General Hospital · NCT07707362 · Data updated 2026-11-12
A virtual, team-based care program tests whether BRIDGE NET can improve care for adults with serious mental illness who are newly diagnosed with cancer.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 248 (estimated) |
| Sponsor | Massachusetts General Hospital Academic / other |
| Locations | 1 site (Boston, Massachusetts) |
| Status | Recruiting |
| Started | October 20, 2026 |
| Main results expected | January 31, 2030 |
| Study ends | July 31, 2030 |
| Registry record updated | November 9, 2026 |
| Trial ID | NCT07707362 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18 and older with a prior diagnosis of serious mental illness and a new, curatively treatable cancer, able to participate within 8 weeks of oncology consultation, and able to read/write in English, Spanish, or Portuguese.
✕Probably not a fit
Patients without a collaboration-ready virtual care setup or those not meeting the inclusion criteria may see no benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a hybrid type I effectiveness-implementation randomized trial to test a virtual BRIDGE NET collaborative care model. The intervention combines early psychiatry input, integrated cancer and mental health treatment planning, and regular outreach to address barriers to care. It targets adults with serious mental illness and a new cancer diagnosis, across multiple cancer types treated with curative intent. The study emphasizes feasibility, real-world delivery, and potential to inform standard-of-care practices. It builds on qualitative input from clinicians and a community advisory board to tailor care for this population.
Why it matters
Potential benefit: If successful, BRIDGE NET could improve treatment access, coordination, and outcomes for patients with SMI who have cancer.
How similar studies have gone: Prior studies suggest collaborative care and virtual delivery can improve cancer and mental health care, but this specific integration for SMI with newly diagnosed cancer is innovative and exploratory.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. be ≥18 years 2. have a prior diagnosis of SMI, defined as schizophrenia spectrum disorder, bipolar disorder, or major depressive disorder with previous psychiatric hospitalization 3. have a new primary diagnosis of invasive breast, head/neck, gastrointestinal (GI), genitourinary (GU), thoracic, or gynecological cancers that can be treated with curative intent 4. be within 8 weeks of initial oncology consultation at or referral to a community cancer affiliate site of the Mass General Brigham Cancer Institute at MGH 5. be able to read and write in English, Spanish, or Portuguese Exclusion Criteria: \-
Where it's running
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Massachusetts General Hospital
Boston, Massachusetts, United States Recruiting
Study contacts
- Study coordinator: Kelly Irwin, MD, MPH
- Email: kirwin1@mgb.org
- Phone: 617-726-2000
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.