Condition

Sarcoma,Soft Tissue clinical trials and research

• 15Clinical trials
• 1New in 30 days
• 16Countries

Newest Sarcoma,Soft Tissue clinical trials

All recruiting trials (15)

• Preventing heart problems in overweight/obese young sarcoma survivors with tirzepatide

  This feasibility study tests whether tirzepatide can be safely given to overweight or obese young adults (18–39) who have completed doxorubicin for soft tissue or bone sarcoma to see if it’s feasible to use in the first year after therapy.

  Recruiting Phase 2 M.D. Anderson Cancer Center · Houston, Texas · NCT07874828

• Personalized PULSAR radiotherapy for advanced small cell lung cancer and brain metastases

  This trial will try personalized PULSAR radiotherapy schedules to see if they are safe and helpful for adults with extensive-stage small cell lung cancer who need thoracic radiation and for adults with 1–5 brain metastases.

  Recruiting Phase 1 University of Texas Southwestern Medical Center · Dallas, Texas · NCT07139990

• Sequential CD146- and HER2-targeted CAR T-cell therapy for advanced sarcoma

  This treatment will test whether giving a patient's own CAR T cells that target CD146 and HER2, one after the other, can shrink tumors in children and adults with relapsed or refractory advanced sarcoma.

  Recruiting Phase 1/2 Essen Biotech · Beijing, Beijing Municipality · NCT07066982

• Preventing wound complications after limb sarcoma surgery with a single-use negative-pressure dressing

  This test will try a single-use negative-pressure wound dressing (PICO14) to see if it reduces wound complications after limb high-grade soft tissue sarcoma surgery in adults who received preoperative radiotherapy.

  Recruiting Istituto Oncologico Veneto IRCCS · Padova, Italy/Padova · NCT06941194

• Total pre-surgery chemotherapy plus regional hyperthermia for high-risk limb and trunk soft tissue sarcoma (TNT-HYPE)

  This trial will test whether giving three cycles of chemotherapy with regional hyperthermia before radiation and surgery is feasible and tolerable for people with high-risk soft tissue sarcoma of the arms, legs, or trunk.

  Recruiting at 8 sites Phase 2 Swiss Cancer Institute · Aarau and 7 other locations · NCT06835049

• Registry for Epithelioid Hemangioendothelioma

  This study is collecting information from people newly diagnosed with epithelioid hemangioendothelioma to better understand the disease and how it’s treated.

  Recruiting at 19 sites Fondazione IRCCS Istituto Nazionale dei Tumori, Milano · Graz, Graz and 21 other locations · NCT06408441

• Comparing a new treatment to standard care for adults with advanced soft tissue sarcomas

  This study is testing a new treatment called INT230-6 to see if it helps adults with advanced soft tissue sarcomas live longer compared to the usual care they receive.

  Recruiting at 17 sites Phase 3 Intensity Therapeutics, Inc. · Los Angeles, California and 16 other locations · NCT06263231

• Combining PARP inhibitors, immunotherapy, and targeted radiation for advanced sarcoma

  This study is testing a new treatment that combines two drugs and targeted radiation to see if it can help people with advanced bone and soft tissue sarcomas feel better and improve their outcomes.

  Recruiting Phase 2 Ruijin Hospital · Shanghai, Shanghai Municipality · NCT06074692

• Combining radioactive seeds and fluzoparib for treating advanced soft tissue sarcoma

  This study is testing if combining radioactive seeds with a medication called fluzoparib can help people with advanced soft tissue sarcoma feel better and have better results than standard treatments.

  Recruiting Phase 2 Sun Yat-sen University · Guangzhou, Guangdong · NCT05894018

• Infusion of engineered lymphocytes for patients with NY-ESO-1 expressing metastatic cancers

  This study is testing a new treatment using specially modified immune cells to see if it can help people with certain advanced cancers that have the NY-ESO-1 marker.

  Recruiting Phase 1/2 Hadassah Medical Organization · Jerusalem · NCT05296564

• Preoperative intensity-modulated radiotherapy with concurrent anlotinib for localized extremity and trunk soft tissue sarcoma

  This test combines preoperative IMRT and the drug anlotinib to see if it improves outcomes for adults with primary soft tissue sarcoma of the arms, legs, or trunk.

  Recruiting Phase 2 Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Beijing, Beijing Municipality · NCT05167994

• Combination treatment of pemetrexed and cisplatin for advanced soft tissue sarcoma

  This study is testing if a combination of two cancer drugs, pemetrexed and cisplatin, can help people with advanced soft tissue sarcoma who haven't responded to standard treatments.

  Recruiting Phase 2 Yonsei University · Seoul · NCT04605770

• Combining Retifanlimab with chemotherapy for advanced soft tissue sarcoma

  This study is testing if adding Retifanlimab to chemotherapy can help people with advanced soft tissue sarcoma fight their cancer better than the usual treatments.

  Recruiting Phase 1/2 Memorial Sloan Kettering Cancer Center · New York, New York · NCT04577014

• Neoadjuvant radiation therapy for retroperitoneal soft tissue sarcoma using protons or carbon ions

  This study is testing whether using proton or carbon ion radiation therapy before surgery can safely help patients with retroperitoneal soft tissue sarcomas.

  Recruiting University Hospital Heidelberg · Heidelberg · NCT04219202

• Registry for patients with sarcoma and carcinosarcoma in Germany

  This study is gathering information from patients with sarcoma and carcinosarcoma in Germany to better understand their treatments and improve care for these rare tumors.

  Recruiting at 21 sites Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest · Tübingen, Baden-Wurttemberg and 20 other locations · NCT04122872

Related topics

Quick answers

How many Sarcoma,Soft Tissue clinical trials are recruiting right now?

15, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 16 countries. The most sites are in United States (4 trials), Germany (4 trials), China (4 trials), Italy (2 trials), France (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 6, Phase 1/2: 3, Phase 3: 1, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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