Registry for patients with sarcoma and carcinosarcoma in Germany
GISAR German Interdisciplinary Sarcoma Registry
This study is gathering information from patients with sarcoma and carcinosarcoma in Germany to better understand their treatments and improve care for these rare tumors.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 9000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest Academic / other |
| Locations | 21 sites (Tübingen, Baden-Wurttemberg and 20 other locations) |
| Trial ID | NCT04122872 on ClinicalTrials.gov |
What this trial studies
The GISAR registry aims to collect comprehensive data on patients diagnosed with sarcoma and carcinosarcoma treated in Germany. It employs an open and modular approach, allowing for both prospective and retrospective data collection to address specific scientific questions regarding treatment effectiveness and adverse effects. By including a diverse patient population, the registry seeks to illuminate the current treatment landscape and improve understanding of various sarcoma subtypes and their management. This initiative is crucial given the rarity and complexity of these tumors, which often require multimodal treatment strategies.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18 and older with histologically verified bone or soft tissue sarcomas or carcinosarcomas.
Not a fit: Patients with non-histologically verified tumors or those under 18 years old may not benefit from this registry.
Why it matters
Potential benefit: If successful, this registry could enhance treatment strategies and outcomes for patients with sarcoma and carcinosarcoma.
How similar studies have performed: While there have been registries for sarcomas, this specific approach focusing on carcinosarcoma is relatively novel and aims to fill existing knowledge gaps.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria:
* Histological verified bone or soft tissue sarcomas including bone and soft tissue tumors with borderline histological results or with unclear histological dignity like giant cell tumors of the bone (GCTB), desmoid tumors, atypical lipomatous tumors etc. - independent of therapy form and therapy line - or Histological verified sarcomatoid carcinomas/ carcinosarcomas: tumors with histological, cytological, or molecular properties of both epithelial tumors ("carcinoma") and mesenchymal tumors ("sarcoma") - independent of therapy form and therapy line.
* Signed informed consent form or equivalent (s. chapter 10)
* Age ≥18 years
Exclusion Criteria:
* none
Where this trial is running
Tübingen, Baden-Wurttemberg and 20 other locations
- Universitätsklinikum Tübingen — Tübingen, Baden-Wurttemberg, Germany (Recruiting)
- Universitätsklinikum Erlangen — Erlangen, Bavaria, Germany (Recruiting)
- HELIOS Klinikum Bad Saarow — Bad Saarow, Germany (Recruiting)
- HELIOS Klinikum Berlin-Buch — Berlin, Germany (Recruiting)
- Vivantes Klinikum Berlin-Spandau — Berlin-Spandau, Germany (Recruiting)
- Universitätsklinikum Erlangen — Erlangen, Germany (Recruiting)
- Klinikum Frankfurt Höchst — Frankfurt, Germany (Recruiting)
- Krankenhaus Nordwest KHNW — Frankfurt, Germany (Recruiting)
- Uniklinik Freiburg — Freiburg im Breisgau, Germany (Recruiting)
- Universitätsmedizin Göttingen — Göttingen, Germany (Recruiting)
- Universitätsmedizin Greifswald — Greifswald, Germany (Recruiting)
- University Hospital Halle (Saale) — Halle, Germany (Recruiting)
- Asklepios Klinik St. Georg — Hamburg, Germany (Recruiting)
- Uniklinikum Leipzig — Leipzig, Germany (Recruiting)
- Universitätsmedizin Mainz — Mainz, Germany (Recruiting)
- Chirurgische Universitätsklinik Mannheim — Mannheim, Germany (Recruiting)
- Westfälische Wilhelms-Universität Münster — Münster, Germany (Recruiting)
- Klinikum Nürnberg — Nuremberg, Germany (Recruiting)
- Barmherzige Brüder Regensburg — Regensburg, Germany (Recruiting)
- Uniklinikum Regensburg — Regensburg, Germany (Recruiting)
- Universitätsklinikum Würzburg — Würzburg, Germany (Recruiting)
Study contacts
- Study coordinator: Daniel Pink, Dr. med.
- Email: daniel.pink@helios-gesundheit.de
- Phone: +49 33631 7
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.