Condition

Resistant Hypertension clinical trials and research

• 8Clinical trials
• 1New in 30 days
• 5Countries

Newest Resistant Hypertension clinical trials

All recruiting trials (8)

• Longer or shorter ablation duration in renal denervation to lower blood pressure

  In people with resistant hypertension, this study tests whether treating the main renal arteries for 2 minutes per site (vs 1 minute) leads to greater blood pressure reduction.

  Recruiting Ruijin Hospital · Shanghai · NCT07876479

• Electrical stimulation plus isometric exercise to improve blood flow in resistant high blood pressure

  This will try whether adding upper‑thoracic electrical stimulation (TENS) and isometric exercise to usual blood pressure medications can lower blood pressure and improve peripheral blood flow in men and women aged 50–60 with resistant hypertension.

  Recruiting Cairo University · Port Said, Port Said Governorate · NCT07383220

• Symplicity Spyral renal denervation in China

  This registry will see if the Symplicity Spyral device is safe and provides lasting blood pressure lowering for people in China who had renal denervation for resistant high blood pressure or who cannot tolerate blood pressure medicines.

  Recruiting Medtronic Vascular · Shanghai, Shanghai Municipality · NCT07081243

• Laparoscopic renal denervation therapy for resistant hypertension

  This study is testing a new procedure to see if it can safely help people with hard-to-treat high blood pressure who are already taking multiple medications.

  Recruiting at 6 sites DeepQure Inc. · Orange, California and 5 other locations · NCT06526858

• Understanding resistant hypertension and its complex interactions

  This study looks at how different body systems interact in people with resistant high blood pressure to better understand why some treatments don't work.

  Recruiting University of Campinas, Brazil · Votuporanga, São Paulo · NCT06450327

• Comparing catecholamine levels in blood during adrenal artery embolization for hypertension

  This study is trying to see how blood pressure changes during a specific treatment for high blood pressure in people with primary aldosteronism and how it relates to certain hormones in the blood.

  Recruiting First Affiliated Hospital of Chengdu Medical College · Chengdu, Sichuan · NCT06228677

• Nitrate supplementation effects on blood pressure in resistant hypertension patients

  This study tests if taking beetroot extract can help lower blood pressure in people with resistant hypertension who haven't changed their blood pressure medications recently.

  Recruiting Early Phase 1 National Institute of Cardiology, Laranjeiras, Brazil · Rio de Janeiro · NCT06169241

• Blocking endothelin-1 receptors to treat resistant high blood pressure

  This tests whether adding bosentan, an endothelin-1 receptor blocker, helps lower blood pressure and improve blood vessel function in adults whose blood pressure stays high despite three medications.

  Recruiting Phase 2 University Hospital, Rouen · Rouen · NCT04388124

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Quick answers

How many Resistant Hypertension clinical trials are recruiting right now?

8, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in China (3 trials), Brazil (2 trials), France (1 trial), Egypt (1 trial), United States (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Early Phase 1: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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