Nitrate supplementation effects on blood pressure in resistant hypertension patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the impact of nitrate supplementation, specifically through beetroot extract, on blood pressure and microvascular function in patients with resistant hypertension. The study aims to determine whether increasing nitric oxide availability can lead to improved vasodilation and overall cardiovascular health. Participants will be randomly assigned to receive either the beetroot extract or a placebo, with careful monitoring of their blood pressure and microvascular responses. The trial focuses on patients who have not altered their antihypertensive medications in the past month.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Resistant hypertension, with a diagnosis described in the medical record, without changing medications or increasing doses in the last 30 days.

Exclusion Criteria:

* neoplasms
* heart failure
* use of medications with nitrate in their formula
* patients undergoing renal denervation

Where it's running

• National Institute of Cardiology
  Rio de Janeiro, Brazil Recruiting

Study contacts

• Study coordinator: EDUARDO TIBIRICA, MD, PhD
• Email: etibi@uol.com.br
• Phone: +55-21-99914-6075

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Electrical stimulation plus isometric exercise to improve blood flow in resistant high blood pressure

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• Breathing muscle training plus dietary nitrate to improve exercise at simulated moderate altitude

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• Symplicity Spyral renal denervation in China

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• Daily peanut consumption for improving health in prediabetes

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  Recruiting Georgia State University · Atlanta, Georgia · NCT06867198

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.