Condition

Recurrent Lung Non-Small Cell Carcinoma clinical trials and research

• 13Clinical trials
• 10Countries

Newest Recurrent Lung Non-Small Cell Carcinoma clinical trials

All recruiting trials (13)

• Advanced NSCLC with actionable mutations after targeted therapy and chemo: expanded Lung-MAP treatment

  This phase II trial tests whether sacituzumab govitecan alone, ivonescimab alone, or the combination of both can help people with advanced or recurrent NSCLC that has a targetable genetic change.

  Recruiting at 41 sites Phase 2 SWOG Cancer Research Network · Berkeley, California and 40 other locations · NCT07393555

• SX-682 with Atezolizumab for advanced or metastatic NSCLC

  This phase 2 trial tests whether combining SX-682 with atezolizumab can help people with advanced, metastatic, or recurrent NSCLC who have progressed after prior treatments.

  Recruiting Phase 2 University of Washington · Seattle, Washington · NCT07322341

• MOv19-BBz CAR T cell treatment for FRa-positive lung cancer

  This trial will test whether a single intrapleural infusion of MOv19-BBz CAR T cells given after lymphodepleting chemotherapy is safe and can help control FRa-positive metastatic or recurrent non-small cell lung cancer with malignant pleural effusion.

  Recruiting Phase 1 University of Pennsylvania · Philadelphia, Pennsylvania · NCT07116057

• Combining cemiplimab with standard treatment for advanced lung cancer

  This study is testing if adding the immunotherapy drug cemiplimab to standard treatments can help people with advanced lung cancer live longer and feel better compared to just the standard treatments alone.

  Recruiting at 399 sites Phase 2/3 SWOG Cancer Research Network · Daphne, Alabama and 412 other locations · NCT06616584

• Predicting how tumors respond to immune therapies using a live diagnostic platform

  This study is testing a new way to predict how well immune therapies will work for patients with different types of solid tumors, including early-stage and metastatic cancers.

  Recruiting at 3 sites Mayo Clinic · Phoenix, Arizona and 2 other locations · NCT06349642

• Targeted treatment for advanced lung cancer with a specific gene change

  This study is testing if a new lung cancer treatment called tepotinib, with or without another drug called ramucirumab, can help people with advanced non-small cell lung cancer that has a specific gene change.

  Recruiting at 246 sites Phase 2 SWOG Cancer Research Network · Daphne, Alabama and 277 other locations · NCT06031688

• Evaluating BDTX-4933 for patients with specific cancer mutations

  This study is testing a new drug called BDTX-4933 to see if it can help adults with advanced cancers that have certain gene mutations feel better and improve their treatment options.

  Recruiting at 34 sites Phase 1/2 Servier · Gilbert, Arizona and 48 other locations · NCT05786924

• Comparing targeted drug combinations for advanced lung cancer with specific gene changes

  This study is testing different combinations of targeted drugs to see if they can help people with advanced lung cancer that has specific gene changes live longer and feel better.

  Recruiting at 372 sites Phase 2 SWOG Cancer Research Network · Daphne, Alabama and 453 other locations · NCT05642572

• Combining SX-682 and Pembrolizumab for Advanced Lung Cancer Treatment

  This study is testing if a new oral medication called SX-682, when combined with the IV drug pembrolizumab, can help people with advanced lung cancer feel better and improve their treatment outcomes.

  Recruiting Phase 2 University of Washington · Seattle, Washington · NCT05570825

• Combining PBF-1129 and Nivolumab for Advanced Lung Cancer Treatment

  This study is testing a new combination of two drugs, PBF-1129 and nivolumab, to see if it can help people with advanced lung cancer live longer and feel better.

  Recruiting Phase 1 Ohio State University Comprehensive Cancer Center · Columbus, Ohio · NCT05234307

• Personalized vaccine treatment for advanced melanoma, breast cancer, and lung cancer

  This study is testing a personalized vaccine combined with a treatment called nivolumab to see if it can help people with advanced melanoma, breast cancer, or lung cancer fight their tumors better.

  Recruiting Phase 1 Fred Hutchinson Cancer Center · Seattle, Washington · NCT05098210

• Investigating PET/CT changes during treatment for advanced lung cancer

  This study is testing how PET and CT scans change during treatment for advanced lung cancer to see if they can help predict how well the treatment is working.

  Recruiting University of Washington · Seattle, Washington · NCT04151940

• Using osimertinib to treat lung cancer with specific genetic mutations

  This study is testing if a medication called osimertinib can help people with advanced lung cancer that has a specific genetic mutation feel better and live longer.

  Recruiting at 215 sites Phase 2 National Cancer Institute (NCI) · Anchorage, Alaska and 346 other locations · NCT03191149

Related topics

Quick answers

How many Recurrent Lung Non-Small Cell Carcinoma clinical trials are recruiting right now?

13, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 10 countries. The most sites are in United States (13 trials), Australia (1 trial), China (1 trial), Denmark (1 trial), France (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 6, Phase 1: 3, Phase 1/2: 1, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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