Condition

BRAF V600 Mutation clinical trials and research

• 5Clinical trials
• 10Countries

Newest BRAF V600 Mutation clinical trials

All recruiting trials (5)

• Dabrafenib and trametinib dose-reduction for BRAF V600 low-grade glioma

  This trial tries to see if stopping or slowly lowering dabrafenib and trametinib after about 12–24 months works for people with BRAF V600–mutant low-grade glioma.

  Recruiting at 12 sites Phase 2 University of California, San Francisco · Birmingham, Alabama and 11 other locations · NCT07110246

• Treatment for patients with BRAFV600E mutant metastatic colorectal cancer

  This study looks at how well current treatments work for patients in China with advanced colorectal cancer that has a specific BRAFV600E mutation.

  Recruiting Fudan University · Shanghai, Shanghai Municipality · NCT06749015

• Neoadjuvant immunotherapy for localized non-small cell lung cancer with rare mutations

  This study is testing if a combination of a new immunotherapy drug and chemotherapy can help people with localized lung cancer that has rare mutations by seeing if it can completely eliminate the tumor.

  Recruiting Phase 2 Guangdong Provincial People's Hospital · Guanzhou, Guangdong · NCT05800340

• Evaluating BDTX-4933 for patients with specific cancer mutations

  This study is testing a new drug called BDTX-4933 to see if it can help adults with advanced cancers that have certain gene mutations feel better and improve their treatment options.

  Recruiting at 34 sites Phase 1/2 Servier · Gilbert, Arizona and 48 other locations · NCT05786924

• Adjuvant therapy for melanoma based on treatment response

  This study tests if a combination of new medications can help people with melanoma who have a specific gene mutation stay cancer-free after their initial treatment.

  Recruiting Early Phase 1 H. Lee Moffitt Cancer Center and Research Institute · Tampa, Florida · NCT04741997

Related topics

Quick answers

How many BRAF V600 Mutation clinical trials are recruiting right now?

5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 10 countries. The most sites are in China (3 trials), United States (3 trials), Australia (1 trial), Denmark (1 trial), France (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 1/2: 1, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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