Molecular Inflammation Board for personalized care of chronic inflammatory diseases
Official title: The Molecular Inflammation Board at the Centers for Personalized Medicine at the University Hospitals of Freiburg, Heidelberg, Tübingen and Ulm - A Multicenter Prospective Observational Study
Run by University Hospital Tuebingen · NCT07132333 · Data updated 2026-11-12
This project collects clinical, lab, imaging, and patient-reported data from adults with psoriasis, psoriatic arthritis, spondyloarthritis, or inflammatory bowel disease who are referred to the Molecular Inflammation Board to see if the board's recommendations influence care and outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 3000 (estimated) |
| Sponsor | University Hospital Tuebingen Academic / other |
| Locations | 1 site (Tübingen) |
| Status | Recruiting |
| Started | November 16, 2022 |
| Main results expected | November 2032 |
| Study ends | November 2032 |
| Registry record updated | August 20, 2025 |
| Trial ID | NCT07132333 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18 years or older) with a chronic inflammatory disorder (psoriasis, psoriatic arthritis, spondyloarthritis, Crohn's disease, or ulcerative colitis) who are referred to the Molecular Inflammation Board and can give informed consent.
✕Probably not a fit
Patients who are not referred to the Molecular Inflammation Board or who lack the capacity to give informed consent will not be included and therefore will not directly benefit from the program's data-driven recommendations.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a prospective, observational program that documents all patients referred to the Molecular Inflammation Board at the Center for Personalized Medicine. It captures clinical outcomes, peripheral immune monitoring, imaging parameters, patient-reported outcomes, and records whether clinicians follow the board's recommendations. The effort is coordinated at University Hospital Tübingen with collaboration from University Hospitals Freiburg, Heidelberg, and Ulm. No experimental treatment is assigned by the program; biologic therapies used in routine care are recorded and analyzed.
Why it matters
Potential benefit: If successful, this work could help tailor treatments more precisely and improve outcomes by identifying which board-guided recommendations lead to better patient results.
How similar studies have gone: Multidisciplinary molecular or inflammation boards and prospective registries have shown promise in improving personalized care in related fields, but robust outcome data specific to this approach in chronic inflammatory diseases remain limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Chronic inflammatory disorder (PsO, PsA, SpA, IBD) * Given informed consent * 18 years of age Exclusion Criteria: * No capacity to consent
Where it's running
-
University Hospital of Tübingen - Center for Personalized Medicine
Tübingen, Germany Recruiting
Study contacts
- Study coordinator: Nisar P Malek, Prof. Dr.
- Email: zpm-meb@med.uni-tuebingen.de
- Phone: +4970712982722
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.