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Probiotics clinical trials and research
As of November 12, 2026, Find a Trial lists 7 Probiotics clinical trials that are recruiting, at sites in 5 countries (most in China (3), Croatia (1), Taiwan (1)). 1 was first registered in the last 30 days. By phase: Phase 4 (2), Phase 2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 7Clinical trials
- 1New in 30 days
- 5Countries
Newest Probiotics clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Probiotics vs Antibiotics as an add-on to non-surgical periodontal care in adult smokers with stage II, grade B periodontitis | — | Cairo | Recruiting | Nov 6, 2026 |
| Clostridium butyricum for anxiety and depression in functional dyspepsia | Phase 4 | Xi’an, Shanxi | Recruiting | Sep 19, 2025 |
| Oral Clostridium butyricum to prevent colorectal adenoma recurrence after removal | Phase 4 | Qingdao, Shandong and 1 other locations | Recruiting | Sep 11, 2025 |
| Coenzyme Q10 toothpaste with daily Limosilactobacillus reuteri probiotics to improve gum health during pregnancy | — | Pavia, Lombardy | Recruiting | Jun 19, 2025 |
| How probiotics affect survival, treatment response, and gut microbiota during cancer therapy | — | New Taipei City | Recruiting | May 31, 2025 |
| Probiotics for treating endometriosis | — | Zagreb | Recruiting | Apr 16, 2025 |
| Using probiotics with immunotherapy for advanced bladder cancer | Phase 2 | Guangzhou, Guangdong and 2 other locations | Recruiting | Apr 1, 2025 |
All recruiting trials (7)
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Probiotics vs Antibiotics as an add-on to non-surgical periodontal care in adult smokers with stage II, grade B periodontitis
This study tests whether systemic probiotics or systemic antibiotics added to standard non-surgical periodontal treatment help improve gum health in adult smokers with stage II, grade B periodontitis.
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Clostridium butyricum for anxiety and depression in functional dyspepsia
This trial will test whether taking the probiotic Clostridium butyricum for four weeks can reduce anxiety and depression symptoms in adults with functional dyspepsia.
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Oral Clostridium butyricum to prevent colorectal adenoma recurrence after removal
This study tests whether a probiotic capsule containing Clostridium butyricum can reduce the chance of colorectal adenomas coming back after they are removed.
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Coenzyme Q10 toothpaste with daily Limosilactobacillus reuteri probiotics to improve gum health during pregnancy
For pregnant women with gum disease, this will try whether adding a CoQ10 toothpaste and daily L. reuteri probiotic to regular cleanings reduces plaque and gum bleeding.
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How probiotics affect survival, treatment response, and gut microbiota during cancer therapy
This test will see if taking a probiotic supplement during cancer treatment helps adults with cancer live longer, respond better to therapy, or have healthier gut bacteria.
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Probiotics for treating endometriosis
This study is testing whether taking specific probiotics can help improve gut health and quality of life for people with endometriosis.
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Using probiotics with immunotherapy for advanced bladder cancer
This study is testing if adding a probiotics treatment to immunotherapy can help people with advanced bladder cancer do better after previous treatments.
Related topics
Quick answers
How many Probiotics clinical trials are recruiting right now?
7, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 5 countries. The most sites are in China (3 trials), Croatia (1 trial), Taiwan (1 trial), Italy (1 trial), Egypt (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 4: 2, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.