Condition

Advanced Urothelial Carcinoma clinical trials and research

• 11Clinical trials
• 3Countries

Newest Advanced Urothelial Carcinoma clinical trials

All recruiting trials (11)

• Rimegepant plus toripalimab in advanced urothelial cancer after standard therapy

  This small, early-stage study tests whether combining rimegepant with toripalimab is safe and shows signs of activity in adults with advanced urothelial cancer that did not respond to prior treatment.

  Recruiting at 2 sites Phase 1 Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Beijing, Beijing Municipality and 1 other locations · NCT07835035

• Trastuzumab Rezetecan with or without Adebrelimab for HER2-expressing advanced urothelial cancer

  This study will test whether Trastuzumab Rezetecan alone or combined with the immunotherapy Adebrelimab helps people with HER2-expressing locally advanced or metastatic urothelial cancer.

  Recruiting at 3 sites Phase 2 Sun Yat-sen University · Guangzhou, Guangdong and 5 other locations · NCT07241793

• Pembrolizumab maintenance after initial enfortumab vedotin plus pembrolizumab for frontline metastatic urothelial cancer

  This trial will test whether continuing pembrolizumab after an 18-week course of enfortumab vedotin plus pembrolizumab helps people with previously untreated metastatic urothelial carcinoma.

  Recruiting Phase 2 Fox Chase Cancer Center · Philadelphia, Pennsylvania · NCT07221942

• Clofarabine treatment for advanced or metastatic urothelial carcinoma

  This study will test whether clofarabine is safe and can shrink tumors in adults with locally advanced or metastatic urothelial carcinoma who have already received or declined standard treatment.

  Recruiting Phase 1/2 Medical University of Vienna · Vienna · NCT07034053

• Using probiotics with immunotherapy for advanced bladder cancer

  This study is testing if adding a probiotics treatment to immunotherapy can help people with advanced bladder cancer do better after previous treatments.

  Recruiting Phase 2 Sun Yat-sen University · Guangzhou, Guangdong and 2 other locations · NCT06904573

• Comparing SHR-A2102 to standard therapies for advanced bladder cancer

  This study is testing a new injectable treatment called SHR-A2102 against standard therapies for people with advanced bladder cancer who have already tried other treatments.

  Recruiting Phase 3 Shanghai Hengrui Pharmaceutical Co., Ltd. · Beijing, Beijing Municipality · NCT06738251

• Evaluating SHR-A2102 with Antitumor Therapy for Advanced Urothelial Carcinoma

  This study is testing a new treatment called SHR-A2102 combined with other therapies to see if it can help patients with advanced urothelial carcinoma who haven't had success with standard treatments.

  Recruiting Phase 1/2 Shanghai Hengrui Pharmaceutical Co., Ltd. · Guangzhou, Guangdong · NCT06639347

• Combining immunotherapy and radiotherapy after surgery for advanced ureter cancer

  This study is testing if combining a new immune treatment with radiation after surgery can help people with advanced ureter cancer do better than just having surgery alone.

  Recruiting at 2 sites Peking University First Hospital · Beijing and 1 other locations · NCT06598761

• Comparing 9MW2821 to chemotherapy for advanced urothelial cancer

  This study tests if a new treatment called 9MW2821 can work better than regular chemotherapy for people with advanced bladder cancer who have already tried other therapies.

  Recruiting Phase 3 Mabwell (Shanghai) Bioscience Co., Ltd. · Shanghai, Shanghai Municipality · NCT06196736

• Combining 9MW2821 and Toripalimab for advanced urothelial cancer

  This study is testing if a new combination of two drugs, 9MW2821 and Toripalimab, can help people with advanced bladder cancer feel better and improve their treatment outcomes.

  Recruiting Phase 1/2 Mabwell (Shanghai) Bioscience Co., Ltd. · Beijing, Beijing Municipality · NCT06079112

• CPI-613 combined with hydroxychloroquine and chemotherapy for advanced solid tumors

  This study is testing a new combination of treatments, including CPI-613 and hydroxychloroquine, to see if it can help people with advanced solid tumors that haven't improved with other chemotherapy.

  Recruiting Phase 2 Northwestern University · Chicago, Illinois · NCT05733000

Related topics

Quick answers

How many Advanced Urothelial Carcinoma clinical trials are recruiting right now?

11, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 3 countries. The most sites are in China (8 trials), United States (2 trials), Austria (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 4, Phase 1/2: 3, Phase 3: 2, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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