Condition

Primary Open Angle Glaucoma (POAG) clinical trials and research

• 10Clinical trials
• 1New in 30 days
• 8Countries

Newest Primary Open Angle Glaucoma (POAG) clinical trials

All recruiting trials (10)

• Pregabalin eye drops vs timolol eye drops for open-angle glaucoma or ocular hypertension

  A doctor-led study tests whether pregabalin eye drops (TB0001) work as well as timolol eye drops to lower eye pressure in adults with glaucoma or high eye pressure.

  Recruiting at 3 sites Phase 2 Tavo Biotherapeutics · Glendale, California and 2 other locations · NCT07913074

• REGN22530 for Adults With Primary Open Angle Glaucoma or Ocular Hypertension

  This study tests REGN22530 in adults with POAG or ocular hypertension to see if it can lower eye pressure and what kind of side effects it may have.

  Recruiting Phase 1/2 Regeneron Pharmaceuticals · Deerfield Beach, Florida · NCT07675824

• Is a preservative-free Bimatoprost 0.01% as effective and safe as Lumigan in POAG or ocular hypertension?

  This study tests whether a preservative-free Bimatoprost 0.01% (YSBP) works as well as Lumigan 0.01% for people with POAG or ocular hypertension.

  Recruiting Phase 3 YS Life Science Co., Ltd. · Beverly Hills, California and 21 other locations · NCT07661329

• Analyzing eye fluid and tissues to find glaucoma-related markers in people with cataracts.

  This study will test whether protein and elemental patterns in eye fluid and tissues taken during cataract surgery differ between people with primary open-angle glaucoma and those without glaucoma.

  Recruiting at 2 sites Military Institute od Medicine National Research Institute · Warsaw and 1 other locations · NCT07462000

• Eye imaging after combined deep sclerectomy and trabeculotomy for open-angle glaucoma

  This study uses ultrasound biomicroscopy to see if specific postoperative eye anatomy after combined deep sclerectomy and trabeculotomy links to better pressure control in people with primary open-angle glaucoma.

  Recruiting Minia University Hospital · Minya, Minya Governorate · NCT07454447

• HUC3-637 for primary open-angle glaucoma and ocular hypertension

  This study tests whether HUC3-637 is safe and can lower eye pressure in adults with primary open-angle glaucoma or ocular hypertension.

  Recruiting Phase 3 Huons Co., Ltd. · Seoul · NCT07335211

• BrudyGlauco (DHA and citicoline) for people with glaucoma

  This trial will test whether taking BrudyGlauco (DHA plus citicoline) for 12 months helps preserve visual field in adults aged 50–75 with glaucoma.

  Recruiting Institut Catala de Retina · Barcelona, Barcelona and 1 other locations · NCT07322965

• Direct Selective Laser Trabeculoplasty to lower eye pressure in non‑Caucasian adults with open-angle glaucoma

  This trial will try Direct Selective Laser Trabeculoplasty (DSLT) to lower eye pressure in adult non‑Caucasian patients with mild to moderate primary open‑angle glaucoma.

  Recruiting Select Eye Care · Elkridge, Maryland · NCT07147647

• GVB-2001 gene therapy injected into the front of the eye for primary open-angle glaucoma

  This will try a gene therapy (GVB-2001) given by intracameral injection to lower high eye pressure in adults with primary open-angle glaucoma.

  Recruiting Phase 1/2 IVIEW Therapeutics Inc. · Suzhou, Jiangsu · NCT06921317

• Investigating oral semaglutide for treating open-angle glaucoma

  This study is testing if a daily pill called semaglutide can help improve vision in people with open-angle glaucoma.

  Recruiting Phase 4 Glostrup University Hospital, Copenhagen · Glostrup Municipality · NCT06792422

Related topics

Quick answers

How many Primary Open Angle Glaucoma (POAG) clinical trials are recruiting right now?

10, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in United States (4 trials), South Korea (1 trial), India (1 trial), Spain (1 trial), China (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 2, Phase 1/2: 2, Phase 4: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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