Comparing Iliopsoas (IPB) and Pericapsular Nerve Group (PENG) blocks for pain control and recovery after total hip replacement

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, double-blind equivalence trial will enroll 118 adults undergoing elective posterior‑approach total hip arthroplasty under spinal anesthesia and randomly assign them to receive either an ultrasound‑guided IPB (7 ml ropivacaine 7.5 mg/ml) or a PENG block (14 ml ropivacaine 3.75 mg/ml) 30 minutes before spinal anesthesia. All patients will receive the same spinal anesthetic and a standardized postoperative analgesic regimen to limit confounding. The primary outcome is pain during early postoperative mobilization measured by patient‑reported pain scores, with secondary endpoints including opioid consumption and recovery measures. Blinding will be maintained for patients, surgeons, and data collectors to ensure unbiased outcome assessment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Adult patients (age \>18 years) ASA physical status classification I-III Scheduled for elective posterior approach total hip arthroplasty (THA) under spinal anesthesia

Exclusion Criteria:

Pregnancy (confirmed by beta-HCG test if applicable) Known peripheral neuropathy or major neurological disease Chronic pain syndromes or long-term opioid use (\>20 mg oral morphine equivalents/day) Severe hepatic or renal insufficiency Allergy to local anesthetics Major coagulopathies Vulnerable patients (e.g., minors, legally protected individuals)

Where it's running

• Liege University Hospital
  Liège, Belgium Recruiting

Study contacts

• Principal investigator: Michele Carella, MD, PhD, ESRA-DRA — Liège University Hospital
• Study coordinator: Michele Carella, MD, PhD, ESRA-DRA
• Email: mcarella@chuliege.be
• Phone: +3242843658

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.