Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Comparison of two chest wall blocks for pain after VATS

Official title: Comparison of the Analgesic Efficacy of Rhomboid Intercostal Plane Block and Serratus Posterior Superior Intercostal Plane Block on Postoperative Pain in Patients Undergoing Video-Assisted Thoracoscopic Surgery

Run by Cumhuriyet University · NCT07524673 · Data updated 2026-11-12

Doctors test whether the rhomboid intercostal plane block or the SPSIP block better relieves pain after video-assisted thoracoscopic surgery in adults.

More Postoperative Pain Management trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment40 (estimated)
SponsorCumhuriyet University
Academic / other
Locations2 sites (Sivas, Merkez and 1 other locations)
StatusRecruiting
StartedMarch 12, 2026
Main results expectedNovember 2026
Study endsDecember 2026
Registry record updatedJune 3, 2026
Trial IDNCT07524673 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults scheduled for elective wedge resection or biopsy via VATS, ASA I–III, without contraindications to regional anesthesia.

Probably not a fit

Patients with high risk for regional blocks or invalid for pain assessment, such as those with skin infection at the site or inability to cooperate, may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized study compares rhomboid intercostal plane (RIB) block with serratus posterior superior intercostal plane block (SPSIPB) for postoperative analgesia after VATS. Blocks are performed after surgery but before waking, with standard analgesic care including paracetamol, dexketoprofen, and patient-controlled tramadol. Outcomes include pain scores at rest and with movement, total tramadol use, side effects, and need for extra analgesia. Primary endpoint is pain intensity (NRS); secondary endpoint is total opioid consumption. The study uses ultrasound guidance and targets specific thoracic levels to create regional anesthesia and maintain comfort after surgery.

Why it matters

Potential benefit: If successful, this approach could improve postoperative pain control and reduce opioid needs after VATS.

How similar studies have gone: Previous regional block comparisons for VATS pain have shown differing effectiveness, making direct comparison valuable but not yet definitive.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Forty adult patients scheduled for elective wedge resection or biopsy under VATS, classified as American Society of Anesthesiologists (ASA) physical status I-III, were enrolled after providing written informed consent.

Exclusion Criteria:

* ASA class IV or higher,
* morbid obesity (BMI \> 40 kg/m²),
* body weight ≤ 50 kg,
* skin infection at the block site,
* refusal to participate,
* inability to cooperate during postoperative pain assessment,
* conversion to open surgery,
* preexisting pain,
* known allergy to any study medication,
* coagulopathy.

Where it's running

  • Sivas Cumhuriyet University School of Medicine, Anesthesiology and Reanimation
    Sivas, Sivas, Turkey (Türkiye)
    Recruiting
  • Sivas Cumhuriyet University
    Sivas, Merkez, Turkey (Türkiye)
    Completed

Study contacts

  • Principal investigator: Oğuz Gündoğdu — Sivas Cumhuriyet University School of Medicine, Anesthesiology and Reanimation
  • Study coordinator: Oğuz Gündoğdu
  • Email: droguzgundogdu@gmail.com
  • Phone: +905545945469

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.