mTLIP versus QIPB for pain relief after lumbar microdiscectomy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized clinical trial will enroll 80 adults (18–65 years, ASA I–III) undergoing elective lumbar microdiscectomy and randomize 40 patients to bilateral ultrasound-guided mTLIP and 40 to bilateral QIPB performed before surgery. The primary outcome is patient-controlled opioid consumption during the first 48 postoperative hours; secondary outcomes include QoR-15 recovery score, static and dynamic NRS pain scores, total rescue analgesic use and time to first rescue, length of hospital stay, perioperative remifentanil dose, and block- or opioid-related side effects. All participants will receive standardized general anesthesia and perioperative care with prospective outcome collection through hospitalization. The trial directly compares an established fascial plane block (mTLIP) with a recently described alternative (QIPB) to determine relative safety and analgesic effectiveness.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age between 18 and 65 years
* Classified as American Society of Anesthesiologists physical status I-III
* Scheduled for elective lumbar microdiscectomy surgery under general anesthesia
* Provision of written informed consent

Exclusion Criteria:

* Use of anticoagulant medications or presence of bleeding diathesis
* Known allergy or hypersensitivity to local anesthetics or opioid drugs
* Infection at the planned block site
* Alcohol or drug dependence
* Cognitive impairment preventing reliable pain assessment
* Pregnancy or lactation
* History of previous lumbar spine surgery
* Diabetes mellitus
* Renal or hepatic insufficiency

Where it's running

• Bursa City Hospital
  Bursa, Nilüfer, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Merih Yildiz Eglen, MD
• Email: meriheg@yahoo.com
• Phone: +905059340629

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.