Condition

Peritoneal Metastases clinical trials and research

• 10Clinical trials
• 3NIH research projects
• 7Countries

Newest Peritoneal Metastases clinical trials

All recruiting trials (10)

• TROP2‑targeted CAR‑NK cells given into the abdomen and vein for colorectal cancer spread to the peritoneum

  We will test whether giving TROP2‑directed CAR‑NK cells both into the abdominal cavity and into a vein, together with cetuximab, is safe and what dose is best for adults with colorectal cancer that has spread to the peritoneum.

  Recruiting Phase 1/2 M.D. Anderson Cancer Center · Houston, Texas · NCT07411599

• Mass-based drug screening to guide personalized HIPEC for high-grade appendiceal and colorectal cancer with peritoneal spread.

  This tests whether a lab-based mass response test on tumor biopsies can pick the best chemotherapy to use during repeated HIPEC for people with unresectable peritoneal metastases from high-grade appendiceal or colorectal cancer.

  Recruiting Yale University · New Haven, Connecticut · NCT07291180

• Direct injection of a modified vaccinia virus (vvDD-hIL2) into abdominal and gastrointestinal tumors

  This trial will try a single direct injection of a modified vaccinia virus (vvDD-hIL2) into abdominal tumors to see if it is safe for adults with advanced metastatic gastrointestinal or peritoneal cancers who have not responded to standard treatments.

  Recruiting Phase 1 Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) · Pittsburgh, Pennsylvania · NCT07001592

• Monitoring blood markers to predict colorectal cancer recurrence after surgery

  This study is testing if blood markers can help predict if colorectal cancer will come back after surgery in patients who have had their cancer completely removed.

  Recruiting Fudan University · Shanghai, Shanghai Municipality · NCT06903325

• Treatment for advanced gastric cancer with peritoneal metastasis using a combination of therapies

  This study is testing a new combination of treatments for people with advanced gastric cancer that has spread to the abdomen to see if it can help slow down the disease and improve their health.

  Recruiting Phase 2 Ruijin Hospital · Shanghai, Huangpu District · NCT06519591

• Using Pressurized Aerosol Chemotherapy for Peritoneal Cancer

  This study is testing a new way to deliver chemotherapy directly into the abdomen to see if it helps people with advanced colorectal, gastric, or pancreatic cancers that can't be surgically removed.

  Recruiting Phase 2 The University of Hong Kong · Hong Kong · NCT06367270

• Understanding biomarkers in metastatic colorectal cancer treatment

  This study is trying to see how cancer changes during treatment in people with metastatic colorectal cancer and whether certain genetic markers can help tailor better treatment options for them.

  Recruiting at 2 sites Region Skane · Lund, Skåne County and 1 other locations · NCT05755672

• Predicting peritoneal metastasis in gastric cancer using radiomics

  This study is testing a new system that uses CT scans to help doctors predict the risk of cancer spreading in patients with advanced gastric cancer.

  Recruiting at 13 sites Chinese Academy of Sciences · Beijing and 12 other locations · NCT05722275

• Treatment for colorectal cancer with hyperthermic chemotherapy

  This study is testing if a new combination of chemotherapy drugs given after surgery can help people with colorectal cancer that has spread to the lining of the abdomen feel better and live longer compared to standard treatment.

  Recruiting at 5 sites Phase 3 Uppsala University · Ahmedabad and 4 other locations · NCT04861558

• Pressurized Chemotherapy for High Risk Colon Cancer Patients

  This study is testing a new type of chemotherapy for patients with high-risk colon cancer to see if it can help prevent cancer from coming back after surgery and standard treatment.

  Recruiting Phase 2 Odense University Hospital · Odense · NCT03280511

NIH-funded research (3)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• TLR-based Nano-therapy delivered into the abdomen to fight peritoneal metastases

  A new nano-therapy given directly into the abdomen uses TLR-agonist–modified particles to target and kill cancer cells in people with peritoneal metastases, especially from ovarian cancer.

  NIH research University of New Mexico Health Scis Ctr · Albuquerque, United States · NIH-11392520

• Nanoparticle immune therapy for cancer spread in the abdomen

  A tiny-particle immune treatment delivered into the abdomen to target ovarian and colorectal cancers that have spread to the peritoneal lining.

  NIH research University of New Mexico Health Scis Ctr · Albuquerque, United States · NIH-11189710

• Using immune therapy to treat cancer spread in the abdomen

  This study is looking at a new way to help people with ovarian and colorectal cancers that have spread to the abdomen by using tiny particles to boost the immune system's ability to fight the cancer directly where it is.

  NIH research University of New Mexico Health Scis Ctr · Albuquerque, United States · NIH-10979697

Related topics

Quick answers

How many Peritoneal Metastases clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in China (3 trials), United States (3 trials), Sweden (2 trials), India (1 trial), Hong Kong (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 3, Phase 1: 1, Phase 1/2: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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