Condition

Liver Metastasis Colon Cancer clinical trials and research

• 20Clinical trials
• 11Countries

Newest Liver Metastasis Colon Cancer clinical trials

All recruiting trials (20)

• Can hepatic artery infusion chemotherapy enable liver surgery for colorectal cancer that has spread to the liver?

  This study tests whether hepatic artery infusion chemotherapy plus standard chemotherapy can make some inoperable colorectal liver metastases operable in patients.

  Recruiting Phase 2 Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT07764497

• Electrochemotherapy for unresectable visceral tumors including liver metastases

  This will try electrochemotherapy with bleomycin in adults who have unresectable primary or metastatic visceral tumors, such as liver metastases.

  Recruiting Istituto Oncologico Veneto IRCCS · Padova · NCT06753136

• Evaluating a new immuno-adjuvant for colorectal liver metastases after ablation treatments

  This study is testing a new treatment called IP-001 to see if it can boost the immune response and help people with colorectal liver metastases feel better after they have undergone ablation therapies.

  Recruiting Phase 1/2 Amsterdam UMC, location VUmc · Amsterdam, North Holland · NCT06630624

• Comparing simultaneous and staged surgery for colorectal cancer with liver metastases

  This study is testing whether doing surgery for colon cancer and liver tumors at the same time or in separate stages is better for patients in terms of recovery and overall health.

  Recruiting Oslo University Hospital · Oslo · NCT06200831

• Comparing two treatments for colorectal liver metastases

  This study is testing whether a new treatment called irreversible electroporation works better than stereotactic body radiotherapy for people with hard-to-treat colorectal cancer that has spread to the liver.

  Recruiting Phase 2/3 Amsterdam UMC, location VUmc · Amsterdam, North Holland · NCT06185556

• Using AI to improve treatment for liver tumors

  This study is testing whether using artificial intelligence can help doctors choose the best treatments and predict outcomes for patients with liver tumors undergoing thermal ablation.

  Recruiting Leiden University Medical Center · Leiden · NCT06179602

• Using high-dose insulin therapy to enhance liver function before surgery

  This study is testing if high-dose insulin therapy can help improve liver function in patients who are about to have major liver surgery.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT06126419

• Evaluating blood tests for detecting residual colorectal cancer

  This study is testing different blood tests to see which ones best help stage III colorectal cancer patients find out if they need more treatment after surgery.

  Recruiting at 14 sites University of Aarhus · Graz, Styria and 14 other locations · NCT06111105

• Comparing methods to increase liver size before surgery

  This study is testing three different ways to help increase liver size before surgery for patients with liver tumors to see which method works best.

  Recruiting Medical University of Warsaw · Warsaw, Masovian Voivodeship · NCT06050200

• Preoperative Ketogenic Diet to Reduce Fat in the Liver Before Surgery

  This study tests whether a short, very low-carbohydrate ketogenic diet before liver surgery can reduce liver fat and improve surgical outcomes for patients with liver metastases from colorectal cancer and NAFLD.

  Recruiting Western University, Canada · London, Ontario · NCT05884723

• Neoadjuvant therapy followed by local treatment for recurrent colorectal liver metastases

  This study is testing if giving a new treatment before local therapy can help people with recurrent colorectal liver cancer live longer compared to getting local therapy right away.

  Recruiting Phase 3 Amsterdam UMC, location VUmc · Amsterdam · NCT05861505

• Using SBRT to treat liver metastases from colorectal cancer after initial treatment

  This study is testing if a special type of radiation therapy can help people with liver tumors from colorectal cancer feel better after their initial treatment.

  Recruiting Phase 2 AHS Cancer Control Alberta · Edmonton, Alberta · NCT05775146

• Understanding biomarkers in metastatic colorectal cancer treatment

  This study is trying to see how cancer changes during treatment in people with metastatic colorectal cancer and whether certain genetic markers can help tailor better treatment options for them.

  Recruiting at 2 sites Region Skane · Lund, Skåne County and 1 other locations · NCT05755672

• Using Gadoxetate MRI to improve detection of liver metastases in colorectal cancer

  This study is testing if a special type of MRI can better identify liver tumors in patients with colorectal cancer to help guide their treatment.

  Recruiting at 2 sites London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · London, Ontario and 1 other locations · NCT05314400

• Living donor liver transplant for patients with non-resectable colorectal cancer liver metastasis

  This study is testing whether living donor liver transplants can help patients with colorectal cancer that has spread to the liver live longer and healthier lives.

  Recruiting Azienda Ospedaliero-Universitaria di Modena · Modena, MO · NCT05186116

• Liver transplantation for patients with non-resectable colorectal liver metastasis

  This study is testing if liver transplants can help people with colorectal cancer that has spread to the liver and can't be removed, to see if it improves their chances of living longer and being cancer-free.

  Recruiting IRCCS Azienda Ospedaliero-Universitaria di Bologna · Bologna · NCT05185245

• Using radiofrequency ablation to boost immune response in colorectal liver cancer patients

  This study is testing if using radiofrequency ablation during surgery can help boost the immune response in patients with colorectal liver cancer to improve their chances of survival.

  Recruiting University of Aarhus · Aarhus · NCT04798898

• Biopsy to study tumor changes after radioembolization

  This study is trying to see how tumors in patients with colorectal cancer that has spread to the liver change after they receive a specific radiation treatment called radioembolization.

  Recruiting Memorial Sloan Kettering Cancer Center · New York, New York · NCT04668872

• Using radiation therapy to treat liver metastases from colorectal cancer

  This study is testing how well Selective Internal Radiation Therapy works for patients with liver cancer that started from colorectal cancer by looking at changes in their blood before and after treatment.

  Recruiting Aarhus University Hospital · Aarhus N, Danmark · NCT04491929

• Microwave ablation for treating small kidney and liver tumors

  This study is testing whether microwave ablation can safely and effectively treat small kidney and liver tumors in patients while they continue their regular care.

  Recruiting IRCCS San Raffaele · Milan · NCT03981497

Related topics

Quick answers

How many Liver Metastasis Colon Cancer clinical trials are recruiting right now?

20, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 11 countries. The most sites are in Canada (5 trials), Italy (4 trials), Netherlands (4 trials), Denmark (3 trials), Sweden (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 3: 1, Phase 1/2: 1, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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