Condition

Out-of-hospital Cardiac Arrest (OHCA) clinical trials and research

• 13Clinical trials
• 10Countries

Newest Out-of-hospital Cardiac Arrest (OHCA) clinical trials

All recruiting trials (13)

• Prehospital femoral arterial access to monitor blood pressure during OHCA

  This pilot study tests whether placing a femoral arterial sheath before hospital arrival is feasible and safe in adults with non-traumatic OHCA to enable invasive blood pressure monitoring and better vasopressor control.

  Recruiting Emergency Medical Service, Prague · Prague · NCT07596446

• Pain after out-of-hospital cardiac arrest and resuscitation

  This study will see if how pain is measured and treated in adults brought back after out-of-hospital cardiac arrest relates to delirium, ICU resource use, and longer-term recovery.

  Recruiting at 3 sites Region Skane · Halmstad and 2 other locations · NCT07564778

• Measuring airway opening during out-of-hospital cardiac arrest

  This project tests whether the Airway Opening Index (AOI) measured from capnograms during CPR in adults with out-of-hospital cardiac arrest is common and linked to return of spontaneous circulation.

  Recruiting University Hospital, Ghent · Ghent, East-Flanders · NCT07438938

• AI-guided chest compressions for personalized CPR

  This project will test an AI app that analyzes arterial pressure waveforms to guide where rescuers compress the chest for adults with out-of-hospital cardiac arrest.

  Recruiting Far Eastern Memorial Hospital · New Taipei City, Banqiao · NCT07431710

• Ventilation Feedback in EMS Resuscitation (ventilation during CPR)

  This trial tests whether real-time visual feedback helps EMS rescuers deliver the right amount of air during CPR in simulated OHCA.

  Recruiting University of Texas Southwestern Medical Center · Dallas, Texas · NCT07352709

• Preventing rearrest after out-of-hospital cardiac arrest with a paramedic post-ROSC care protocol

  This project will test whether a structured prehospital post-resuscitation protocol delivered by paramedics can lower the chance of rearrest in adults who regain a pulse after out-of-hospital cardiac arrest.

  Recruiting Phase 2/3 Siriraj Hospital · Bangkok Noi, Bangkok · NCT07239908

• Using Positive End-Expiratory Pressure during CPR for Cardiac Arrest

  This study is testing if using a special breathing technique during CPR can help adults who have a cardiac arrest outside of the hospital survive better and have good brain function afterwards.

  Recruiting at 6 sites Phase 3 University Hospital, Ghent · Ostend, West-Flandres and 6 other locations · NCT06939335

• Comparing hypothermia and normal temperature after cardiac arrest treatment

  This study is testing whether cooling the body or keeping it at normal temperature after cardiac arrest helps patients recover better and live longer.

  Recruiting at 27 sites Kagawa University · Kurume, Fukuoka and 28 other locations · NCT06776549

• Using ketamine for sedation to protect the brain after cardiac arrest

  This study is testing if using ketamine as a sedative can better protect the brains of adults who have survived a cardiac arrest compared to the usual sedative, propofol.

  Recruiting Phase 2 Copenhagen University Hospital, Rigshospitalet · Copenhagen and 1 other locations · NCT06744361

• Emergency total ECLS vs standard ACLS with bailout ECMO for OHCA survival

  This trial tests whether starting total extracorporeal life support early helps adults with witnessed OHCA survive with good brain function better than starting standard ACLS and adding ECMO only if needed.

  Recruiting at 2 sites Taipei Medical University Shuang Ho Hospital · New Taipei, Taiwan and 1 other locations · NCT06692075

• Using Transesophageal Echocardiography for Cardiac Arrest Patients

  This study is testing if a special ultrasound called Transesophageal Echocardiography can help doctors find out why some people have a cardiac arrest outside the hospital, to improve their chances of recovery.

  Recruiting Far Eastern Memorial Hospital · New Taipei City · NCT06672315

• Optimizing blood flow to protect the brain after cardiac arrest

  This study is testing a personalized blood pressure management plan to see if it can help protect the brains of people who have had a cardiac arrest.

  Recruiting National University Hospital, Singapore · Singapore · NCT05679739

• Effects of mean arterial pressure on outcomes after out-of-hospital cardiac arrest

  This study tests if keeping blood pressure at a higher level after a cardiac arrest can help patients recover better and survive longer.

  Recruiting at 28 sites Centre Hospitalier le Mans · Montpellier, Sarthe and 30 other locations · NCT05486884

Related topics

Quick answers

How many Out-of-hospital Cardiac Arrest (OHCA) clinical trials are recruiting right now?

13, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 10 countries. The most sites are in Taiwan (3 trials), France (2 trials), Belgium (2 trials), Japan (1 trial), Thailand (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2/3: 1, Phase 3: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →