Measuring airway opening during out-of-hospital cardiac arrest

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This retrospective observational cohort uses capnography recordings from about 150 adult out-of-hospital cardiac arrest cases logged in the Lazarus database at Ghent University Hospital. The Airway Opening Index (AOI) will be calculated from capnograms obtained immediately after intubation to quantify airway closure during CPR. The analysis will report AOI prevalence, examine correlations between AOI and return of spontaneous circulation (ROSC), and explore how applied positive airway pressures relate to AOI and outcomes. Results are intended to clarify whether AOI can serve as a CPR quality metric or prognostic indicator.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult (over 18 years old) patients with out-of-hospital cardiac arrest.
* Patients undergoing cardiopulmonary resuscitation (CPR).
* Patients who were intubated and had available capnogram recordings immediately after intubation.

Exclusion Criteria:

* Patients that were not intubated
* Patients that did not receive CPR following intubation
* Cases with a technical challenge with the ETCO₂ measurement (i.e., issues with waveform data of the capnogram.

Where it's running

• Ghent University Hospital
  Ghent, East-Flanders, Belgium Recruiting

Study contacts

• Study coordinator: Said Hachimi Idrissi, MD, PhD
• Email: SAID.HACHIMIIDRISSI@ugent.be
• Phone: 0032 9 332 50 24

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.