Condition

Mesothelioma, Malignant clinical trials and research

• 10Clinical trials
• 9Countries

Newest Mesothelioma, Malignant clinical trials

All recruiting trials (10)

• Partial pleurectomy to relieve symptoms from unresectable pleural mesothelioma.

  The team will try a limited partial pleurectomy and decortication to reduce chest symptoms and improve quality of life for people with epithelioid pleural mesothelioma that cannot be completely removed.

  Recruiting University of Chicago · Chicago, Illinois · NCT07126509

• Local anesthesia thoracoscopy for diagnosing pleural effusion

  This study tests if using local anesthesia during a thoracoscopy can help diagnose suspected cancer-related fluid buildup in the chest faster and more comfortably than standard tests.

  Recruiting National and Kapodistrian University of Athens · Athens, Attica · NCT06946498

• SW-682 for advanced solid tumors

  This study is testing a new oral treatment called SW-682 to see if it can help adults with advanced solid tumors that haven't improved with other therapies.

  Recruiting at 8 sites Phase 1 Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany · Scottsdale, Arizona and 7 other locations · NCT06251310

• Additional chemotherapy after surgery for malignant peritoneal mesothelioma

  This study is testing whether giving chemotherapy directly into the abdomen or through an IV after surgery helps people with malignant peritoneal mesothelioma do better.

  Recruiting at 9 sites Phase 2 Memorial Sloan Kettering Cancer Center · Chicago, Illinois and 12 other locations · NCT06057935

• Evaluating a new CAR T-cell therapy for solid tumors expressing MSLN

  This study is testing a new CAR T-cell therapy to see if it can safely treat adults with solid tumors like colorectal and lung cancer that express a specific protein.

  Recruiting at 12 sites Phase 1/2 A2 Biotherapeutics Inc. · Gilbert, Arizona and 11 other locations · NCT06051695

• Evaluating HTL0039732 for Advanced Solid Tumours

  This study is testing a new drug called HTL0039732, alone and with another treatment, to see if it can help people with advanced solid tumors by boosting their immune response against cancer.

  Recruiting at 6 sites Phase 1/2 Cancer Research UK · Cambridge and 5 other locations · NCT05944237

• Treatment for advanced cancers expressing mesothelin

  This study is testing a new treatment called SynKIR-110 to see if it is safe and works for people with advanced cancers that have a specific protein called mesothelin, like ovarian cancer and mesothelioma.

  Recruiting at 4 sites Phase 1 Verismo Therapeutics · Tampa, Florida and 4 other locations · NCT05568680

• Combining Sintilimab, Anlotinib, and Chemotherapy for Advanced Pleural Mesothelioma

  This study is testing a new combination of Sintilimab, Anlotinib, and chemotherapy to see if it helps people with advanced pleural mesothelioma who haven't had treatment before.

  Recruiting at 2 sites Phase 2 Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Taiyuan, Shanxi and 1 other locations · NCT05188859

• Analyzing solid tumors for HLA loss and collecting T cells for CAR T-cell therapy

  This study is testing how often solid tumors lose a key protein that helps the immune system recognize them, while also collecting T cells from patients with high-risk cancers to prepare for future CAR T-cell therapy.

  Recruiting at 13 sites A2 Biotherapeutics Inc. · Gilbert, Arizona and 15 other locations · NCT04981119

• Tulmimetostat treatment for advanced solid tumors and lymphomas

  This study is testing a new treatment called Tulmimetostat to see if it can help people with advanced solid tumors and lymphomas feel better and fight their cancer.

  Recruiting at 43 sites Phase 1/2 Novartis · Tampa, Florida and 79 other locations · NCT04104776

Related topics

Quick answers

How many Mesothelioma, Malignant clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in United States (7 trials), United Kingdom (2 trials), China (1 trial), Greece (1 trial), France (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1/2: 3, Phase 1: 2, Phase 2: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →