A study on brain health and aging in Bordeaux.

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the determinants and natural history of brain aging in a representative sample of 2000 individuals aged 55 and older from the Bordeaux metropolitan area. It employs molecular epidemiology methods to explore various factors, including nutrition, that may influence cognitive aging and the onset of dementia. Participants will undergo a series of assessments, including questionnaires and biological sample collections, to gather comprehensive data on their health and environmental exposures. The study seeks to enhance understanding of cognitive aging and inform prevention strategies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

For the main study:

1. live in Bordeaux metropolitan area,
2. be between 55 and 80 years old (included),
3. selected in terms of socioeconomic level, according to a sampling strategy by age groups and income categories representative of the general population between 55 and 80 years of age
4. be affiliated with the social security system,
5. agree to take a blood sample for the biobank.

For the MRI sub-study: be between 55 and 75 years old (included). Inclusion criteria for the immune response substudy: be 70 years of age or older or participate in the MRI study; agree to take a supplemental blood sample for this substudy.

Exclusion Criteria:

For the main study: persons under guardianship (or more generally under protection), unable to give consent to participate.

For the MRI sub-study: have a contraindication to MRI examination (pacemaker, a valve prosthesis or any other internal electrical/magnetic device; history of neurosurgery or aneurysm; claustrophobia; presence of metal fragments in the eyes, brain or spinal cord).

Where it's running

• University Hospital of Bordeaux
  Bordeaux, Bordeaux, France Recruiting

Study contacts

• Principal investigator: Cécilia SAMIERI, Dr — Bordeaux Population Health Researh Center Inserm
• Study coordinator: Cécilia SAMIERI, Dr
• Email: cecilia.samieri@u-bordeaux.fr
• Phone: 5 57 57 45 15

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.