Exploring brain structure and gene expression in mental disorders

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the relationship between brain structure, function, and gene expression in patients with schizophrenia and other mental disorders. Participants aged 13-35 will undergo baseline and follow-up assessments while adhering to their prescribed medications for one year. The goal is to identify biological markers and understand how gene-environment interactions affect brain networks, which could enhance the understanding of schizophrenia's neuropathological basis.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age: 13-35 years old(Patients with healthy siblings can be extended to 14-35 years of age)
* Course of disease: \<24 months
* Priority is given to patients who have never taken medicine or duration of drug use \< 2 weeks
* No nuclear magnetic contraindications.

Exclusion Criteria:

* Family history of psychotic disorders, history of psychoactive substances abuse, alcohol dependence, or nicotine dependence
* Have a major physical disease or infectious disease
* History of coma and serious neurological disease 4.MRI contraindications.

Where it's running

• The Second Xiangya hospital of central south univerity
  Changsha, Hunan, China Recruiting

Study contacts

• Study coordinator: Yunzhi Pan
• Email: panyunzhi@csu.edu.cn
• Phone: 15074818197

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.