Improving chronic pain care with mindfulness and management visits

Optimizing Chronic Pain Care With Mindfulness and Chronic Pain Management Visits

Phase 3 Interventional University of Utah · NCT06387290

This study is testing if combining mindfulness practices with personalized pain management visits can help people with chronic pain feel better and reduce their reliance on opioids.

Quick facts

PhasePhase 3
Study typeInterventional
Enrollment300 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Utah Academic / other
Locations3 sites (La Jolla, California and 2 other locations)
Trial IDNCT06387290 on ClinicalTrials.gov

What this trial studies

This trial aims to evaluate the effectiveness of Mindfulness-Oriented Recovery Enhancement (MORE) and patient-centered chronic pain management visits in primary care settings. The focus is on reducing chronic pain, enhancing quality of life, and minimizing opioid-related harms for patients on long-term opioid therapy. Participants will engage in mindfulness practices and receive tailored management visits to address their pain and opioid use. The study will assess the impact of these interventions on patient outcomes over time.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18 and older with a chronic pain diagnosis and current opioid use for at least three months.

Not a fit: Patients with chronic pain due to cancer or those with active suicidal intent or severe psychiatric disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve pain management and quality of life for patients with chronic pain while reducing reliance on opioids.

How similar studies have performed: Other studies have shown promise in using mindfulness-based interventions for chronic pain management, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 18 +
* Current chronic pain diagnosis (pain for ≥3 months) determined by physician assessment
* Prescribed long-term opioid therapy (≥3 months)
* Score \>=3 on the Pain Enjoyment General Activity scale
* Score \>=9 on the Current Opioid Misuse Measure OR lifetime psychiatric or substance use disorder diagnosis OR benzodiazepine use OR history of overdose OR patient or physician determination that risks of opioid use may outweigh the benefits of opioid use

Exclusion Criteria:

* Chronic pain due to a cancer diagnosis
* Active suicidal intent, schizophrenia, psychotic disorder
* Prior experience with Mindfulness-Based Stress Reduction, Mindfulness-Based Cognitive Therapy, Mindfulness-Based Relapse Prevention, or Mindfulness-Oriented Recovery Enhancement

Where this trial is running

La Jolla, California and 2 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Chronic PainPrescription Opioid MisuseSubstance-Related DisordersPainNarcotic-Related DisordersChemically-Induced DisordersMental DisordersOpioid-Related Disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.